Solute carrier family 25 (mitochondrial carrier, Aralar), member 12
type: Thing
description: mammalian protein found in Mus musculus
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P361
  value: mitochondrial carrier
additional property: PropertyValue
  property ID: P361
  value: mitochondrial carrier domain superfamily
additional property: PropertyValue
  property ID: P361
  value: EF-hand domain pair
additional property: PropertyValue
  property ID: P527
  value: EF-hand 1, calcium-binding site
additional property: PropertyValue
  property ID: P527
  value: Mitochondrial substrate/solute carrier
additional property: PropertyValue
  property ID: P527
  value: EF-hand domain
additional property: PropertyValue
  property ID: P637
  value: NP_766024
additional property: PropertyValue
  property ID: P637
  value: XP_011238155
additional property: PropertyValue
  property ID: P637
  value: XP_030108114
additional property: PropertyValue
  property ID: P680
  value: calcium ion binding
additional property: PropertyValue
  property ID: P680
  value: metal ion binding
additional property: PropertyValue
  property ID: P680
  value: L-glutamate transmembrane transporter activity
additional property: PropertyValue
  property ID: P681
  value: mitochondrial inner membrane
additional property: PropertyValue
  property ID: P681
  value: myelin sheath
additional property: PropertyValue
  property ID: P681
  value: membrane
additional property: PropertyValue
  property ID: P682
  value: response to calcium ion
additional property: PropertyValue
  property ID: P682
  value: malate-aspartate shuttle
additional property: PropertyValue
  property ID: P682
  value: transmembrane transport
additional property: PropertyValue
  property ID: P702
  value: Slc25a12
additional property: PropertyValue
  property ID: P703
  value: house mouse
additional property: PropertyValue
  property ID: P705
  value: ENSMUSP00000139371
additional property: PropertyValue
  property ID: P705
  value: ENSMUSP00000122103
confidence:
  popularity graph score:
    score: 0.002
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 17
      unique citations norm: 0.007
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 17
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: Q8BH59
    source count: 1
    confidence: 0.2
  P361:
    value: Q425007
    source count: 1
    confidence: 0.2
    value label: mitochondrial carrier
  P361:
    value: Q24778220
    source count: 1
    confidence: 0.2
    value label: mitochondrial carrier domain superfamily
  P361:
    value: Q24742069
    source count: 1
    confidence: 0.2
    value label: EF-hand domain pair
  P361:
    value: Q83134678
    source count: 1
    confidence: 0.2
    value label: EF-hand domain, protein family
  P361:
    value: Q95352992
    source count: 1
    confidence: 0.2
    value label: EF-Hand 1, calcium-binding site, protein family
  P527:
    value: Q24738895
    source count: 1
    confidence: 0.2
    value label: EF-hand 1, calcium-binding site
  P527:
    value: Q24783799
    source count: 1
    confidence: 0.2
    value label: Mitochondrial substrate/solute carrier
  P527:
    value: Q24723907
    source count: 1
    confidence: 0.2
    value label: EF-hand domain
  P637:
    value: NP_766024
    source count: 1
    confidence: 0.2
  P637:
    value: XP_011238155
    source count: 1
    confidence: 0.2
  P637:
    value: XP_030108114
    source count: 1
    confidence: 0.2
  P680:
    value: Q14633862
    source count: 4
    confidence: 0.8
    value label: calcium ion binding
  P680:
    value: Q13667380
    source count: 1
    confidence: 0.2
    value label: metal ion binding
  P680:
    value: Q14905282
    source count: 4
    confidence: 0.8
    value label: L-glutamate transmembrane transporter activity
  P680:
    value: Q14905290
    source count: 4
    confidence: 0.8
    value label: L-aspartate transmembrane transporter activity
  P680:
    value: Q14887309
    source count: 1
    confidence: 0.2
    value label: transmembrane transporter activity
  P681:
    value: Q14330614
    source count: 3
    confidence: 0.6
    value label: mitochondrial inner membrane
  P681:
    value: Q187388
    source count: 1
    confidence: 0.2
    value label: myelin sheath
  P681:
    value: Q14349455
    source count: 1
    confidence: 0.2
    value label: membrane
  P681:
    value: Q39572
    source count: 7
    confidence: 1.0
    value label: mitochondrion
  P681:
    value: Q14327652
    source count: 2
    confidence: 0.4
    value label: integral component of membrane
  P682:
    value: Q14865231
    source count: 3
    confidence: 0.6
    value label: response to calcium ion

value: Q903660
source count: 4
confidence: 0.8
value label: malate-aspartate shuttle

value: Q14820680
source count: 1
confidence: 0.2
value label: transmembrane transport

value: Q14905285
source count: 3
confidence: 0.6
value label: L-glutamate transmembrane transport

value: Q14905291
source count: 4
confidence: 0.8
value label: aspartate transmembrane transport

value: Q18269582
source count: 1
confidence: 0.2
value label: Slc25a12

value: Q83310
source count: 1
confidence: 0.2
value label: house mouse

value: ENSMUSP00000139371
source count: 1
confidence: 0.2

value: ENSMUSP00000122103
source count: 1
confidence: 0.2

source: GOA
stated in qid: Q28018111
retrieved: 2019-02-14

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2019-02-14

source: Slc25a13-knockout mice harbor metabolic deficits but fail to display hallmarks of adult-onset type II citrullinemia
stated in qid: Q28506798
retrieved: 2018-02-27

source: GOA
stated in qid: Q28018111
retrieved: 2018-02-27

source: Proteomic analysis of the mouse liver mitochondrial inner membrane
stated in qid: Q28587359
retrieved: 2018-02-27

source: Proteolipid protein is required for transport of sirtuin 2 into CNS myelin
stated in qid: Q28587657
retrieved: 2018-02-27

source: Ca2+ Activation kinetics of the two aspartate-glutamate mitochondrial carriers, aralar and citrin: role in the heart malate-aspartate NADH shuttle
stated in qid: Q28512011
retrieved: 2018-02-27

source: A mitochondrial protein compendium elucidates complex I disease biology
stated in qid: Q24655079
retrieved: 2018-02-27

source: Ca2+ Activation kinetics of the two aspartate-glutamate mitochondrial carriers, aralar and citrin: role in the heart malate-aspartate NADH shuttle
stated in qid: Q28512011
retrieved: 2019-02-14

source: Slc25a13-knockout mice harbor metabolic deficits but fail to display hallmarks of adult-onset type II citrullinemia
stated in qid: Q28506798
retrieved: 2019-02-14

source: A mitochondrial protein compendium elucidates complex I disease biology
stated in qid: Q24655079
retrieved: 2019-02-14

source: Proteomic analysis of the mouse liver mitochondrial inner membrane
stated in qid: Q28587359
retrieved: 2019-02-14

source: Proteolipid protein is required for transport of sirtuin 2 into CNS myelin
stated in qid: Q28587657
retrieved: 2019-02-14

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2022-05-25

source: Q20641742
stated in qid: Q20641742
retrieved: 2022-03-20

source: ensembl Release 106
stated in qid: Q111699881

wikidata id: Q21498120
domain: protein
level: standard
html url: https://4ort.xyz/entity/solute-carrier-family-25-mitochondrial-carrier-aralar-member-12
markdown url: https://4ort.xyz/entity/solute-carrier-family-25-mitochondrial-carrier-aralar-member-12.md
facts url summary: https://4ort.xyz/entity/solute-carrier-family-25-mitochondrial-carrier-aralar-member-12/facts.json
facts url standard: https://4ort.xyz/entity/solute-carrier-family-25-mitochondrial-carrier-aralar-member-12/facts.json
facts url full: https://4ort.xyz/entity/solute-carrier-family-25-mitochondrial-carrier-aralar-member-12/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-11T06:32:48.254148Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T14:12:18.107337+00:00Z