Solute carrier family 25 member 12
type: Thing
description: mammalian protein found in Homo sapiens
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P352
  value: O75746
additional property: PropertyValue
  property ID: P361
  value: mitochondrial carrier
additional property: PropertyValue
  property ID: P361
  value: EF-hand domain pair
additional property: PropertyValue
  property ID: P361
  value: mitochondrial carrier domain superfamily
additional property: PropertyValue
  property ID: P527
  value: EF-hand domain
additional property: PropertyValue
  property ID: P527
  value: EF-hand 1, calcium-binding site
additional property: PropertyValue
  property ID: P527
  value: Mitochondrial substrate/solute carrier
additional property: PropertyValue
  property ID: P637
  value: NP_003696
additional property: PropertyValue
  property ID: P637
  value: XP_011510372
additional property: PropertyValue
  property ID: P638
  value: 4P60
additional property: PropertyValue
  property ID: P638
  value: 4P5X
additional property: PropertyValue
  property ID: P680
  value: calcium ion binding
additional property: PropertyValue
  property ID: P680
  value: metal ion binding
additional property: PropertyValue
  property ID: P680
  value: L-aspartate transmembrane transporter activity
additional property: PropertyValue
  property ID: P681
  value: membrane
additional property: PropertyValue
  property ID: P681
  value: myelin sheath
additional property: PropertyValue
  property ID: P681
  value: mitochondrion
additional property: PropertyValue
  property ID: P682
  value: gluconeogenesis
additional property: PropertyValue
  property ID: P682
  value: malate-aspartate shuttle
additional property: PropertyValue
  property ID: P682
  value: response to calcium ion
additional property: PropertyValue
  property ID: P702
  value: SLC25A12
additional property: PropertyValue
  property ID: P703
  value: Homo sapiens
additional property: PropertyValue
  property ID: P705
  value: ENSP00000388658
additional property: PropertyValue
  property ID: P705
  value: ENSP00000263812
additional property: PropertyValue
  property ID: P705
  value: ENSP00000413968
additional property: PropertyValue
  property ID: P7260
  value: 2.A.29.14.1
confidence:
  popularity graph score:
    score: 0.002
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 15
      unique citations norm: 0.006
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 15
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: O75746
    source count: 1
    confidence: 0.2
  P361:
    value: Q425007
    source count: 2
    confidence: 0.4
    value label: mitochondrial carrier
  P361:
    value: Q24742069
    source count: 1
    confidence: 0.2
    value label: EF-hand domain pair
  P361:
    value: Q24778220
    source count: 1
    confidence: 0.2
    value label: mitochondrial carrier domain superfamily
  P361:
    value: Q83134678
    source count: 1
    confidence: 0.2
    value label: EF-hand domain, protein family
  P361:
    value: Q95352992
    source count: 1
    confidence: 0.2
    value label: EF-Hand 1, calcium-binding site, protein family
  P527:
    value: Q24723907
    source count: 1
    confidence: 0.2
    value label: EF-hand domain
  P527:
    value: Q24738895
    source count: 1
    confidence: 0.2
    value label: EF-hand 1, calcium-binding site
  P527:
    value: Q24783799
    source count: 1
    confidence: 0.2
    value label: Mitochondrial substrate/solute carrier
  P637:
    value: NP_003696
    source count: 1
    confidence: 0.2
  P637:
    value: XP_011510372
    source count: 1
    confidence: 0.2
  P638:
    value: 4P60
    source count: 1
    confidence: 0.2
  P638:
    value: 4P5X
    source count: 1
    confidence: 0.2
  P680:
    value: Q14633862
    source count: 3
    confidence: 0.6
    value label: calcium ion binding
  P680:
    value: Q13667380
    source count: 1
    confidence: 0.2
    value label: metal ion binding
  P680:
    value: Q14905290
    source count: 1
    confidence: 0.2
    value label: L-aspartate transmembrane transporter activity
  P680:
    value: Q14905282
    source count: 1
    confidence: 0.2
    value label: L-glutamate transmembrane transporter activity
  P680:
    value: Q22324830
    source count: 1
    confidence: 0.2
    value label: acidic amino acid transmembrane transporter activity
  P681:
    value: Q14349455
    source count: 1
    confidence: 0.2
    value label: membrane
  P681:
    value: Q187388
    source count: 1
    confidence: 0.2
    value label: myelin sheath

value: Q39572
source count: 5
confidence: 1.0
value label: mitochondrion

value: Q14330614
source count: 4
confidence: 0.8
value label: mitochondrial inner membrane

value: Q14327652
source count: 3
confidence: 0.6
value label: integral component of membrane

value: Q191835
source count: 1
confidence: 0.2
value label: gluconeogenesis

value: Q903660
source count: 2
confidence: 0.4
value label: malate-aspartate shuttle

value: Q14865231
source count: 1
confidence: 0.2
value label: response to calcium ion

value: Q14820680
source count: 1
confidence: 0.2
value label: transmembrane transport

value: Q14905291
source count: 1
confidence: 0.2
value label: aspartate transmembrane transport

value: Q18033146
source count: 1
confidence: 0.2
value label: SLC25A12

value: Q15978631
source count: 1
confidence: 0.2
value label: Homo sapiens

value: ENSP00000388658
source count: 1
confidence: 0.2

value: ENSP00000263812
source count: 1
confidence: 0.2

value: ENSP00000413968
source count: 1
confidence: 0.2

value: ENSP00000437845
source count: 1
confidence: 0.2

value: 2.A.29.14.1
source count: 2
confidence: 0.4

source: GOA
stated in qid: Q28018111
retrieved: 2019-04-08

source: Molecular cloning of Aralar, a new member of the mitochondrial carrier superfamily that binds calcium and is present in human muscle and brain
stated in qid: Q24309242
retrieved: 2019-04-08

source: Calcium-induced conformational changes of the regulatory domain of human mitochondrial aspartate/glutamate carriers.
stated in qid: Q30604103
retrieved: 2019-04-08

source: Citrin and aralar1 are Ca(2+)-stimulated aspartate/glutamate transporters in mitochondria
stated in qid: Q24291715
retrieved: 2017-09-26

source: GOA
stated in qid: Q28018111
retrieved: 2018-01-01

source: Citrin and aralar1 are Ca(2+)-stimulated aspartate/glutamate transporters in mitochondria
stated in qid: Q24291715
retrieved: 2019-04-08

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2019-04-08

source: Molecular cloning of Aralar, a new member of the mitochondrial carrier superfamily that binds calcium and is present in human muscle and brain
stated in qid: Q24309242
retrieved: 2017-09-26

source: Phosphoproteome analysis of functional mitochondria isolated from resting human muscle reveals extensive phosphorylation of inner membrane protein complexes and enzymes
stated in qid: Q24299408
retrieved: 2017-09-26

source: Phosphoproteome analysis of functional mitochondria isolated from resting human muscle reveals extensive phosphorylation of inner membrane protein complexes and enzymes
stated in qid: Q24299408
retrieved: 2019-04-08

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2019-11-13

source: Q20641742
stated in qid: Q20641742
retrieved: 2020-05-30

source: Transporter Classification database
stated in qid: Q142667
retrieved: 2020-03-13

source: Ensembl Release 99
stated in qid: Q83867711

wikidata id: Q22683554
domain: protein
level: standard
html url: https://4ort.xyz/entity/solute-carrier-family-25-member-12-q22683554
markdown url: https://4ort.xyz/entity/solute-carrier-family-25-member-12-q22683554.md
facts url summary: https://4ort.xyz/entity/solute-carrier-family-25-member-12-q22683554/facts.json
facts url standard: https://4ort.xyz/entity/solute-carrier-family-25-member-12-q22683554/facts.json
facts url full: https://4ort.xyz/entity/solute-carrier-family-25-member-12-q22683554/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-08T00:14:44.191328Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T14:41:09.338404+00:00Z