Solute carrier family 22 (organic anion transporter), member 6
type: Thing
description: mammalian protein found in Mus musculus
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P361
  value: organic cation transport protein/SVOP
additional property: PropertyValue
  property ID: P361
  value: MFS transporter superfamily
additional property: PropertyValue
  property ID: P361
  value: Major facilitator superfamily domain
additional property: PropertyValue
  property ID: P527
  value: major facilitator superfamily domain
additional property: PropertyValue
  property ID: P637
  value: NP_032792
additional property: PropertyValue
  property ID: P680
  value: transmembrane transporter activity
additional property: PropertyValue
  property ID: P680
  value: inorganic anion exchanger activity
additional property: PropertyValue
  property ID: P680
  value: urate transmembrane transporter activity
additional property: PropertyValue
  property ID: P681
  value: integral component of membrane
additional property: PropertyValue
  property ID: P681
  value: membrane
additional property: PropertyValue
  property ID: P681
  value: integral component of plasma membrane
additional property: PropertyValue
  property ID: P682
  value: response to methotrexate
additional property: PropertyValue
  property ID: P682
  value: renal tubular secretion
additional property: PropertyValue
  property ID: P682
  value: anion transport
additional property: PropertyValue
  property ID: P702
  value: Slc22a6
additional property: PropertyValue
  property ID: P703
  value: house mouse
additional property: PropertyValue
  property ID: P705
  value: ENSMUSP00000010250
confidence:
  popularity graph score:
    score: 0.002
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 13
      unique citations norm: 0.005
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 13
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: Q8VC69
    source count: 1
    confidence: 0.2
  P361:
    value: Q24768092
    source count: 1
    confidence: 0.2
    value label: organic cation transport protein/SVOP
  P361:
    value: Q41797380
    source count: 1
    confidence: 0.2
    value label: MFS transporter superfamily
  P361:
    value: Q83133864
    source count: 1
    confidence: 0.2
    value label: Major facilitator superfamily domain
  P527:
    value: Q24722244
    source count: 1
    confidence: 0.2
    value label: major facilitator superfamily domain
  P637:
    value: NP_032792
    source count: 1
    confidence: 0.2
  P680:
    value: Q14887309
    source count: 1
    confidence: 0.2
    value label: transmembrane transporter activity
  P680:
    value: Q14877691
    source count: 4
    confidence: 0.8
    value label: inorganic anion exchanger activity
  P680:
    value: Q21109072
    source count: 1
    confidence: 0.2
    value label: urate transmembrane transporter activity
  P680:
    value: Q21111552
    source count: 3
    confidence: 0.6
    value label: sodium-independent organic anion transmembrane transporter activity
  P680:
    value: Q21108814
    source count: 5
    confidence: 1.0
    value label: organic anion transmembrane transporter activity
  P681:
    value: Q14327652
    source count: 2
    confidence: 0.4
    value label: integral component of membrane
  P681:
    value: Q14349455
    source count: 1
    confidence: 0.2
    value label: membrane
  P681:
    value: Q14859540
    source count: 4
    confidence: 0.8
    value label: integral component of plasma membrane
  P681:
    value: Q14864700
    source count: 3
    confidence: 0.6
    value label: basolateral plasma membrane
  P681:
    value: Q29548
    source count: 3
    confidence: 0.6
    value label: plasma membrane
  P682:
    value: Q14819383
    source count: 1
    confidence: 0.2
    value label: response to methotrexate
  P682:
    value: Q21111551
    source count: 3
    confidence: 0.6
    value label: renal tubular secretion
  P682:
    value: Q14877696
    source count: 1
    confidence: 0.2
    value label: anion transport
  P682:
    value: Q21104647
    source count: 3
    confidence: 0.6
    value label: alpha-ketoglutarate transport
  P682:
    value: Q14820680
    source count: 1
    confidence: 0.2
    value label: transmembrane transport
  P702:
    value: Q18252844
    source count: 1
    confidence: 0.2
    value label: Slc22a6
  P703:
    value: Q83310
    source count: 1
    confidence: 0.2
    value label: house mouse
  P705:
    value: ENSMUSP00000010250
    source count: 1
    confidence: 0.2
citations:
  source: GOA
  stated in qid: Q28018111
  retrieved: 2019-05-09

source: GOA
stated in qid: Q28018111
retrieved: 2018-04-24

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2019-05-09

source: Identification and functional assessment of the novel murine organic anion transporter Oat5 (Slc22a19) expressed in kidney
stated in qid: Q28576093
retrieved: 2019-05-09

source: IRIP, a new ischemia/reperfusion-inducible protein that participates in the regulation of transporter activity
stated in qid: Q24307952
retrieved: 2019-05-09

source: Liver X receptor activation downregulates organic anion transporter 1 (OAT1) in the renal proximal tubule
stated in qid: Q24299777
retrieved: 2019-05-09

source: Developmentally regulated expression of organic ion transporters NKT (OAT1), OCT1, NLT (OAT2), and Roct
stated in qid: Q28508498
retrieved: 2019-05-09

source: Molecular cloning and characterization of NKT, a gene product related to the organic cation transporter family that is almost exclusively expressed in the kidney
stated in qid: Q28592258
retrieved: 2019-05-09

source: Role of glycosylation in the organic anion transporter OAT1
stated in qid: Q24306516
retrieved: 2019-05-09

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2022-05-25

source: Q20641742
stated in qid: Q20641742
retrieved: 2022-03-20

source: ensembl Release 106
stated in qid: Q111699881

wikidata id: Q21990588
domain: protein
level: standard
html url: https://4ort.xyz/entity/solute-carrier-family-22-organic-anion-transporter-member-6
markdown url: https://4ort.xyz/entity/solute-carrier-family-22-organic-anion-transporter-member-6.md
facts url summary: https://4ort.xyz/entity/solute-carrier-family-22-organic-anion-transporter-member-6/facts.json
facts url standard: https://4ort.xyz/entity/solute-carrier-family-22-organic-anion-transporter-member-6/facts.json
facts url full: https://4ort.xyz/entity/solute-carrier-family-22-organic-anion-transporter-member-6/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-11T21:51:07.620036Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T13:58:59.184953+00:00Z