Solute carrier family 16 member 1
type: Thing
description: mammalian protein found in Rattus norvegicus
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P352
  value: P53987
additional property: PropertyValue
  property ID: P361
  value: Monocarboxylate transporter 1
additional property: PropertyValue
  property ID: P361
  value: MFS transporter superfamily
additional property: PropertyValue
  property ID: P361
  value: Major facilitator superfamily domain
additional property: PropertyValue
  property ID: P527
  value: major facilitator superfamily domain
additional property: PropertyValue
  property ID: P637
  value: NP_036848
additional property: PropertyValue
  property ID: P637
  value: XP_038957688
additional property: PropertyValue
  property ID: P680
  value: protein binding
additional property: PropertyValue
  property ID: P680
  value: monocarboxylic acid transmembrane transporter activity
additional property: PropertyValue
  property ID: P680
  value: lactate transmembrane transporter activity
additional property: PropertyValue
  property ID: P681
  value: centrosome
additional property: PropertyValue
  property ID: P681
  value: plasma membrane
additional property: PropertyValue
  property ID: P681
  value: integral component of plasma membrane
additional property: PropertyValue
  property ID: P682
  value: lipid metabolism
additional property: PropertyValue
  property ID: P682
  value: centrosome cycle
additional property: PropertyValue
  property ID: P682
  value: monocarboxylic acid transport
additional property: PropertyValue
  property ID: P702
  value: Slc16a1
additional property: PropertyValue
  property ID: P703
  value: brown rat
additional property: PropertyValue
  property ID: P705
  value: ENSRNOP00000027234
additional property: PropertyValue
  property ID: P705
  value: ENSRNOP00000092404
confidence:
  popularity graph score:
    score: 0.002
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 11
      unique citations norm: 0.004
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 11
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: P53987
    source count: 1
    confidence: 0.2
  P361:
    value: Q24780351
    source count: 1
    confidence: 0.2
    value label: Monocarboxylate transporter 1
  P361:
    value: Q41797380
    source count: 1
    confidence: 0.2
    value label: MFS transporter superfamily
  P361:
    value: Q83133864
    source count: 1
    confidence: 0.2
    value label: Major facilitator superfamily domain
  P527:
    value: Q24722244
    source count: 1
    confidence: 0.2
    value label: major facilitator superfamily domain
  P637:
    value: NP_036848
    source count: 1
    confidence: 0.2
  P637:
    value: XP_038957688
    source count: 1
    confidence: 0.2
  P680:
    value: Q167149
    source count: 4
    confidence: 0.8
    value label: protein binding
  P680:
    value: Q21100315
    source count: 2
    confidence: 0.4
    value label: monocarboxylic acid transmembrane transporter activity
  P680:
    value: Q21100314
    source count: 1
    confidence: 0.2
    value label: lactate transmembrane transporter activity
  P680:
    value: Q14860823
    source count: 1
    confidence: 0.2
    value label: symporter activity
  P680:
    value: Q14762996
    source count: 1
    confidence: 0.2
    value label: protein homodimerization activity
  P681:
    value: Q190769
    source count: 1
    confidence: 0.2
    value label: centrosome
  P681:
    value: Q29548
    source count: 4
    confidence: 0.8
    value label: plasma membrane
  P681:
    value: Q14859540
    source count: 5
    confidence: 1.0
    value label: integral component of plasma membrane
  P681:
    value: Q14349455
    source count: 1
    confidence: 0.2
    value label: membrane
  P681:
    value: Q14327652
    source count: 2
    confidence: 0.4
    value label: integral component of membrane
  P682:
    value: Q2792936
    source count: 1
    confidence: 0.2
    value label: lipid metabolism
  P682:
    value: Q5063037
    source count: 1
    confidence: 0.2
    value label: centrosome cycle
  P682:
    value: Q21100317
    source count: 2
    confidence: 0.4
    value label: monocarboxylic acid transport
  P682:
    value: Q14877632
    source count: 1
    confidence: 0.2
    value label: response to food
  P682:
    value: Q22290448
    source count: 2
    confidence: 0.4
    value label: lactate transmembrane transport
  P702:
    value: Q24390725
    source count: 1
    confidence: 0.2
    value label: Slc16a1
  P703:
    value: Q184224
    source count: 1
    confidence: 0.2
    value label: brown rat

value: ENSRNOP00000027234
source count: 1
confidence: 0.2

value: ENSRNOP00000092404
source count: 1
confidence: 0.2

source: The role of charged residues in the transmembrane helices of monocarboxylate transporter 1 and its ancillary protein basigin in determining plasma membrane expression and catalytic activity
stated in qid: Q24319749
retrieved: 2019-04-08

source: Fluorescence resonance energy transfer studies on the interaction between the lactate transporter MCT1 and CD147 provide information on the topology and stoichiometry of the complex in situ
stated in qid: Q28576944
retrieved: 2019-04-08

source: Colocalization of MCT1, CD147, and LDH in mitochondrial inner membrane of L6 muscle cells: evidence of a mitochondrial lactate oxidation complex
stated in qid: Q28574030
retrieved: 2019-04-08

source: GOA
stated in qid: Q28018111
retrieved: 2019-04-08

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2019-04-08

source: Studies on the DIDS-binding site of monocarboxylate transporter 1 suggest a homology model of the open conformation and a plausible translocation cycle
stated in qid: Q28580055
retrieved: 2019-04-08

source: AR-C155858 is a potent inhibitor of monocarboxylate transporters MCT1 and MCT2 that binds to an intracellular site involving transmembrane helices 7-10
stated in qid: Q28580635
retrieved: 2019-04-08

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2022-05-25

source: Q20641742
stated in qid: Q20641742
retrieved: 2022-03-20

source: ensembl Release 106
stated in qid: Q111699881

wikidata id: Q28562589
domain: protein
level: standard
html url: https://4ort.xyz/entity/solute-carrier-family-16-member-1-q28562589
markdown url: https://4ort.xyz/entity/solute-carrier-family-16-member-1-q28562589.md
facts url summary: https://4ort.xyz/entity/solute-carrier-family-16-member-1-q28562589/facts.json
facts url standard: https://4ort.xyz/entity/solute-carrier-family-16-member-1-q28562589/facts.json
facts url full: https://4ort.xyz/entity/solute-carrier-family-16-member-1-q28562589/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-08T18:28:05.133749Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T15:13:18.529887+00:00Z