# Sodium voltage-gated channel alpha subunit 8

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21135479](https://www.wikidata.org/wiki/Q21135479)  
**Source**: https://4ort.xyz/entity/sodium-voltage-gated-channel-alpha-subunit-8-q21135479


## References

1. UniProt
2. IUPHAR/BPS Guide to PHARMACOLOGY
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q9UQD0)
4. Q20641742
5. [Swiss-Prot](http://www.uniprot.org/uniprot/Q9WTU3.txt?version=127)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQD0)
7. [Pathogenic mechanism of recurrent mutations of SCN8A in epileptic encephalopathy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQD0)
8. [Identifying a kinase network regulating FGF14:Nav1.6 complex assembly using split-luciferase complementation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQD0)
9. [Bioluminescence methodology for the detection of protein-protein interactions within the voltage-gated sodium channel macromolecular complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQD0)
10. [Exon organization, coding sequence, physical mapping, and polymorphic intragenic markers for the human neuronal sodium channel gene SCN8A](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UQD0&geneProductId=UniProtKB:Q9UQD0)
11. [De novo gain-of-function and loss-of-function mutations ofSCN8Ain patients with intellectual disabilities and epilepsy](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UQD0&geneProductId=UniProtKB:Q9UQD0)
12. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UQD0&geneProductId=UniProtKB:Q9UQD0)
13. [Addition of positive charges at the C-terminal peptide region of CssII, a mammalian scorpion peptide toxin, improves its affinity for sodium channels Nav1.6](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UQD0&geneProductId=UniProtKB:Q9UQD0)
14. [Characterization of a de novo SCN8A mutation in a patient with epileptic encephalopathy](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UQD0&geneProductId=UniProtKB:Q9UQD0)
15. [Exon organization, coding sequence, physical mapping, and polymorphic intragenic markers for the human neuronal sodium channel gene SCN8A](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQD0)
16. [De novo gain-of-function and loss-of-function mutations ofSCN8Ain patients with intellectual disabilities and epilepsy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQD0)
17. [Characterization of a de novo SCN8A mutation in a patient with epileptic encephalopathy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQD0)
18. [Addition of positive charges at the C-terminal peptide region of CssII, a mammalian scorpion peptide toxin, improves its affinity for sodium channels Nav1.6](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQD0)
19. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQD0)
20. Ensembl Release 99
21. Identifiers.org
22. Transporter Classification database