# Sodium channel epithelial 1 subunit gamma

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21135432](https://www.wikidata.org/wiki/Q21135432)  
**Source**: https://4ort.xyz/entity/sodium-channel-epithelial-1-subunit-gamma


## References

1. UniProt
2. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL585)
3. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL1398126)
4. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P51170)
5. Q20641742
6. [Mechanism by which Liddle's syndrome mutations increase activity of a human epithelial Na+ channel](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51170)
7. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51170)
8. [Proteolytic activation of the epithelial sodium channel (ENaC) by the cysteine protease cathepsin-S](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51170)
9. [The Nedd4-like protein KIAA0439 is a potential regulator of the epithelial sodium channel](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51170)
10. [Regulation of epithelial sodium channel trafficking by proprotein convertase subtilisin/kexin type 9 (PCSK9)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51170)
11. [Delta-subunit confers novel biophysical features to alpha beta gamma-human epithelial sodium channel (ENaC) via a physical interaction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51170)
12. [Atomic force microscopy reveals the architecture of the epithelial sodium channel (ENaC)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51170)
13. [Human Nedd4 interacts with the human epithelial Na+ channel: WW3 but not WW1 binds to Na+-channel subunits](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51170)
14. [A novel splice-site mutation in the gamma subunit of the epithelial sodium channel gene in three pseudohypoaldosteronism type 1 families](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51170)
15. [Identification of the SPLUNC1 ENaC-inhibitory domain yields novel strategies to treat sodium hyperabsorption in cystic fibrosis airway epithelial cultures](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51170)
16. [Identification and proteomic profiling of exosomes in human urine](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51170)
17. Ensembl Release 99
18. Transporter Classification database