# SMCR8-C9orf72 complex subunit

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21135644](https://www.wikidata.org/wiki/Q21135644)  
**Source**: https://4ort.xyz/entity/smcr8-c9orf72-complex-subunit-q21135644


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q8TEV9)
3. Q20641742
4. [C9orf72 binds SMCR8, localizes to lysosomes, and regulates mTORC1 signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TEV9)
5. [The C9orf72-interacting protein Smcr8 is a negative regulator of autoimmunity and lysosomal exocytosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TEV9)
6. [Pooled‐matrix protein interaction screens using Barcode Fusion Genetics](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TEV9)
7. [Loss of C9ORF72 impairs autophagy and synergizes with polyQ Ataxin‐2 to induce motor neuron dysfunction and cell death](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TEV9)
8. [Multiplex image-based autophagy RNAi screening identifies SMCR8 as ULK1 kinase activity and gene expression regulator](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TEV9)
9. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TEV9)
10. [The ALS/FTLD associated protein C9orf72 associates with SMCR8 and WDR41 to regulate the autophagy-lysosome pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TEV9)
11. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8TEV9&geneProductId=UniProtKB:Q8TEV9)
12. Ensembl Release 99