# Small ubiquitin-like modifier 1

> mammalian protein found in Mus musculus

**Wikidata**: [Q15333187](https://www.wikidata.org/wiki/Q15333187)  
**Source**: https://4ort.xyz/entity/small-ubiquitin-like-modifier-1-q15333187


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P63166)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63166)
5. [Sumoylation activates the transcriptional activity of Pax-6, an important transcription factor for eye and brain development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63166)
6. [SUMOylation of Tr2 orphan receptor involves Pml and fine-tunes Oct4 expression in stem cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63166)
7. [PIASy-mediated sumoylation of SREBP1c regulates hepatic lipid metabolism upon fasting signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63166)
8. [Ikaros SUMOylation: switching out of repression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63166)
9. [Regulation of protein tyrosine phosphatase 1B by sumoylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63166)
10. [Retinoic acid-stimulated sequential phosphorylation, PML recruitment, and SUMOylation of nuclear receptor TR2 to suppress Oct4 expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63166)
11. [Intracellular trafficking of heat shock factor 2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63166)
12. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63166)
13. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63166&geneProductId=UniProtKB:P63166)
14. [Complex SUMO-1 regulation of cardiac transcription factor Nkx2-5](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63166&geneProductId=UniProtKB:P63166)
15. [Ikaros SUMOylation: switching out of repression](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63166&geneProductId=UniProtKB:P63166)
16. [BCL11A is a SUMOylated protein and recruits SUMO-conjugation enzymes in its nuclear body](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63166)
17. [p73 and p63 protein stability: the way to regulate function?](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63166&geneProductId=UniProtKB:P63166)
18. [Polycomb protein SCML2 associates with USP7 and counteracts histone H2A ubiquitination in the XY chromatin during male meiosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63166)
19. [Complex SUMO-1 regulation of cardiac transcription factor Nkx2-5](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63166)
20. [p73 and p63 protein stability: the way to regulate function?](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63166)
21. [Loss of SUMO1 in mice affects RanGAP1 localization and formation of PML nuclear bodies, but is not lethal as it can be compensated by SUMO2 or SUMO3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63166)
22. [SUMO1-dependent modulation of SERCA2a in heart failure](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63166)
23. [SUMO1 haploinsufficiency leads to cleft lip and palate](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63166)
24. [Loss of SUMO1 in mice affects RanGAP1 localization and formation of PML nuclear bodies, but is not lethal as it can be compensated by SUMO2 or SUMO3](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63166&geneProductId=UniProtKB:P63166)
25. [Intracellular trafficking of heat shock factor 2](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63166&geneProductId=UniProtKB:P63166)
26. [Dual modification of BMAL1 by SUMO2/3 and ubiquitin promotes circadian activation of the CLOCK/BMAL1 complex](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63166&geneProductId=UniProtKB:P63166)
27. [Dual modification of BMAL1 by SUMO2/3 and ubiquitin promotes circadian activation of the CLOCK/BMAL1 complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63166)
28. ensembl Release 106