# Slit guidance ligand 2

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21135631](https://www.wikidata.org/wiki/Q21135631)  
**Source**: https://4ort.xyz/entity/slit-guidance-ligand-2-q21135631


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O94813)
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/H0Y9Z6)
4. Q20641742
5. [Cloning and expressions of three mammalian homologues of Drosophila slit suggest possible roles for Slit in the formation and maintenance of the nervous system](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94813)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94813)
7. [A molecular mechanism for the heparan sulfate dependence of slit-robo signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94813)
8. [Structure and functional relevance of the Slit2 homodimerization domain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94813)
9. [The axonal repellent, Slit2, inhibits directional migration of circulating neutrophils](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94813)
10. [Neuronal chemorepellent Slit2 inhibits vascular smooth muscle cell migration by suppressing small GTPase Rac1 activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94813)
11. [Slit proteins bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94813)
12. [Structural insights into the Slit-Robo complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94813)
13. [Extracellular Ig domains 1 and 2 of Robo are important for ligand (Slit) binding](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94813)
14. [Characterization of Slit protein interactions with glypican-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94813)
15. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94813)
16. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:H0Y9Z6)
17. [Novel regulated expression of the SLIT/ROBO pathway in the ovary: possible role during luteolysis in women](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94813)
18. [Slit proteins bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance](http://www.ebi.ac.uk/QuickGO/annotations?protein=O94813&geneProductId=UniProtKB:O94813)
19. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?protein=O94813&geneProductId=UniProtKB:O94813)
20. [Proteomic analysis of podocyte exosome-enriched fraction from normal human urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=O94813&geneProductId=UniProtKB:O94813)
21. [The Slit/Robo system suppresses hepatocyte growth factor-dependent invasion and morphogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94813)
22. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94813)
23. [Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94813)
24. [SLITs suppress tumor growth in vivo by silencing Sdf1/Cxcr4 within breast epithelium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94813)
25. [Slit proteins are not dominant chemorepellents for olfactory tract and spinal motor axons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94813)
26. [SLIT2-mediated ROBO2 signaling restricts kidney induction to a single site](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94813)
27. [Squeezing axons out of the gray matter: a role for slit and semaphorin proteins from midline and ventral spinal cord](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94813)
28. [Slit2-Mediated chemorepulsion and collapse of developing forebrain axons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94813)
29. [HDAC5 is a repressor of angiogenesis and determines the angiogenic gene expression pattern of endothelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94813)
30. [SLITs suppress tumor growth in vivo by silencing Sdf1/Cxcr4 within breast epithelium](http://www.ebi.ac.uk/QuickGO/annotations?protein=O94813&geneProductId=UniProtKB:O94813)
31. [The neuronal repellent Slit inhibits leukocyte chemotaxis induced by chemotactic factors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94813)
32. [Axonal growth regulation of fetal and embryonic stem cell-derived dopaminergic neurons by Netrin-1 and Slits](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94813)
33. [Structure and functional relevance of the Slit2 homodimerization domain](http://www.ebi.ac.uk/QuickGO/annotations?protein=O94813&geneProductId=UniProtKB:O94813)
34. [Slit2 is a repellent for retinal ganglion cell axons](http://www.ebi.ac.uk/QuickGO/annotations?protein=O94813&geneProductId=UniProtKB:O94813)
35. [Slit2 is a repellent for retinal ganglion cell axons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94813)
36. Ensembl Release 99