# SLC9A3 regulator 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21112493](https://www.wikidata.org/wiki/Q21112493)  
**Source**: https://4ort.xyz/entity/slc9a3-regulator-1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O14745)
3. Q20641742
4. [NHERF1/EBP50 head-to-tail intramolecular interaction masks association with PDZ domain ligands](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14745)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14745)
6. [The β2-adrenergic receptor interacts with the Na+/H+-exchanger regulatory factor to control Na+/H+ exchange](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14745)
7. [PTEN tumor suppressor associates with NHERF proteins to attenuate PDGF receptor signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14745)
8. [The PDZ-binding chloride channel ClC-3B localizes to the Golgi and associates with cystic fibrosis transmembrane conductance regulator-interacting PDZ proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14745)
9. [Inhibition of T cell activation by cyclic adenosine 5'-monophosphate requires lipid raft targeting of protein kinase A type I by the A-kinase anchoring protein ezrin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14745)
10. [An isoform-specific PDZ-binding motif targets type I PIP5 kinase beta to the uropod and controls polarization of neutrophil-like HL60 cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14745)
11. [Identification of EPI64, a TBC/rabGAP domain-containing microvillar protein that binds to the first PDZ domain of EBP50 and E3KARP](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14745)
12. [Isoforms of SLC26A6 mediate anion transport and have functional PDZ interaction domains](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14745)
13. [MCC, a new interacting protein for Scrib, is required for cell migration in epithelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14745)
14. [Phosphorylation of PDZ1 domain attenuates NHERF-1 binding to cellular targets](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14745)
15. [Podocalyxin EBP50 ezrin molecular complex enhances the metastatic potential of renal cell carcinoma through recruiting Rac1 guanine nucleotide exchange factor ARHGEF7](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14745)
16. [A new human NHERF1 mutation decreases renal phosphate transporter NPT2a expression by a PTH-independent mechanism](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14745)
17. [An AP-MS- and BioID-compatible MAC-tag enables comprehensive mapping of protein interactions and subcellular localizations](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14745)
18. [The EBP50-moesin interaction involves a binding site regulated by direct masking on the FERM domain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14745)
19. [Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14745)
20. [A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14745)
21. [Structural basis for NHERF recognition by ERM proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14745)
22. [Breast cancer-derived K172N, D301V mutations abolish Na+/H+ exchanger regulatory factor 1 inhibition of platelet-derived growth factor receptor signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14745)
23. [NHE-RF, a Regulatory Cofactor for Na+-H+Exchange, Is a Common Interactor for Merlin and ERM (MERM) Proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14745)
24. [A C-terminal motif found in the β 2 -adrenergic receptor, P2Y1 receptor and cystic fibrosis transmembrane conductance regulator determines binding to the Na + /H + exchanger regulatory factor family of PDZ proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14745)
25. [PTEN, NHERF1 and PHLPP form a tumor suppressor network that is disabled in glioblastoma](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14745)
26. [A novel association of mGluR1a with the PDZ scaffold protein CAL modulates receptor activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14745)
27. [Dynamic regulation of cystic fibrosis transmembrane conductance regulator by competitive interactions of molecular adaptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14745)
28. [Defining the human deubiquitinating enzyme interaction landscape](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14745)
29. [Analysis of protein-protein interactions in cross-talk pathways reveals CRKL protein as a novel prognostic marker in hepatocellular carcinoma](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14745)
30. [PDZK1 directly regulates the function of organic cation/carnitine transporter OCTN2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14745)
31. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O14745&geneProductId=UniProtKB:O14745)
32. [A kinase-regulated mechanism controls CFTR channel gating by disrupting bivalent PDZ domain interactions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14745)
33. [Modulation of renal apical organic anion transporter 4 function by two PDZ domain-containing proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14745)
34. [Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense](http://www.ebi.ac.uk/QuickGO/annotations?protein=O14745&geneProductId=UniProtKB:O14745)
35. [NHERF1/EBP50 controls morphogenesis of 3D colonic glands by stabilizing PTEN and ezrin-radixin-moesin proteins at the apical membrane](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14745)
36. [Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)](http://www.ebi.ac.uk/QuickGO/annotations?protein=O14745&geneProductId=UniProtKB:O14745)
37. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?protein=O14745&geneProductId=UniProtKB:O14745)
38. [MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=O14745&geneProductId=UniProtKB:O14745)
39. [In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=O14745&geneProductId=UniProtKB:O14745)
40. [Proteomic analysis of podocyte exosome-enriched fraction from normal human urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=O14745&geneProductId=UniProtKB:O14745)
41. [Loss of PTEN binding adapter protein NHERF1 from plasma membrane in glioblastoma contributes to PTEN inactivation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14745)
42. [Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14745)
43. [MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14745)
44. [In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14745)
45. [Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14745)
46. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14745)
47. [EBP50 exerts tumor suppressor activity by promoting cell apoptosis and retarding extracellular signal-regulated kinase activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14745)
48. [The scaffolding protein EBP50 regulates microvillar assembly in a phosphorylation-dependent manner](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14745)
49. [NHERF1 mutations and responsiveness of renal parathyroid hormone](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14745)
50. Ensembl Release 99