# SKI proto-oncogene

> mammalian protein found in Homo sapiens

**Wikidata**: [Q14913250](https://www.wikidata.org/wiki/Q14913250)  
**Source**: https://4ort.xyz/entity/ski-proto-oncogene


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P12755)
3. Q20641742
4. [Ski is involved in transcriptional regulation by the repressor and full-length forms of Gli3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755)
5. [Involvement of the constitutive complex formation of c-Ski/SnoN with Smads in the impaired negative feedback regulation of transforming growth factor beta signaling in scleroderma fibroblasts](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755)
6. [The Ski protein family is required for MeCP2-mediated transcriptional repression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755)
7. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755)
8. [Structural mechanism of Smad4 recognition by the nuclear oncoprotein Ski: insights on Ski-mediated repression of TGF-beta signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755)
9. [The Ski oncoprotein interacts with Skip, the human homolog of Drosophila Bx42](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755)
10. [Complex formation between proteins encoded by the ski gene family](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755)
11. [Ski regulates muscle terminal differentiation by transcriptional activation of Myog in a complex with Six1 and Eya3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755)
12. [SKI and MEL1 cooperate to inhibit transforming growth factor-beta signal in gastric cancer cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755)
13. [Ski co-repressor complexes maintain the basal repressed state of the TGF-beta target gene, SMAD7, via HDAC3 and PRMT5](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755)
14. [Identification of novel Smad2 and Smad3 associated proteins in response to TGF-beta1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755)
15. [Protooncogene Ski cooperates with the chromatin-remodeling factor Satb2 in specifying callosal neurons.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755)
16. [Rnf165/Ark2C Enhances BMP-Smad Signaling to Mediate Motor Axon Extension](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755)
17. [Inhibiting Drivers of Non-mutational Drug Tolerance Is a Salvage Strategy for Targeted Melanoma Therapy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755)
18. [Intercellular variation in signaling through the TGF-β pathway and its relation to cell density and cell cycle phase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755)
19. [The Ski-binding protein C184M negatively regulates tumor growth factor-beta signaling by sequestering the Smad proteins in the cytoplasm](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755)
20. [Functional proteomics mapping of a human signaling pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755)
21. [Ski is a component of the histone deacetylase complex required for transcriptional repression by Mad and thyroid hormone receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755)
22. [DACH1 inhibits transforming growth factor-beta signaling through binding Smad4](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755)
23. [Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755)
24. [c-Ski inhibits the TGF-beta signaling pathway through stabilization of inactive Smad complexes on Smad-binding elements](http://www.ebi.ac.uk/QuickGO/annotations?protein=P12755&geneProductId=UniProtKB:P12755)
25. [Involvement of the constitutive complex formation of c-Ski/SnoN with Smads in the impaired negative feedback regulation of transforming growth factor beta signaling in scleroderma fibroblasts](http://www.ebi.ac.uk/QuickGO/annotations?protein=P12755&geneProductId=UniProtKB:P12755)
26. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P12755&geneProductId=UniProtKB:P12755)
27. [Requirement of the co-repressor homeodomain-interacting protein kinase 2 for ski-mediated inhibition of bone morphogenetic protein-induced transcriptional activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755)
28. [Arkadia induces degradation of SnoN and c-Ski to enhance transforming growth factor-beta signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755)
29. [A census of human transcription factors: function, expression and evolution](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755)
30. [c-Ski inhibits the TGF-beta signaling pathway through stabilization of inactive Smad complexes on Smad-binding elements](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755)
31. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755)
32. [Role of PML and PML-RARalpha in Mad-mediated transcriptional repression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755)
33. [Identification of Ski as a target for Aurora A kinase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755)
34. [Nuclear and cytoplasmic c-Ski differently modulate cellular functions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755)
35. [SKI activates Wnt/beta-catenin signaling in human melanoma](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755)
36. [SKI and MEL1 cooperate to inhibit transforming growth factor-beta signal in gastric cancer cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P12755&geneProductId=UniProtKB:P12755)
37. [Nuclear and cytoplasmic c-Ski differently modulate cellular functions](http://www.ebi.ac.uk/QuickGO/annotations?protein=P12755&geneProductId=UniProtKB:P12755)
38. [The protooncogene Ski controls Schwann cell proliferation and myelination](http://www.ebi.ac.uk/QuickGO/annotations?protein=P12755&geneProductId=UniProtKB:P12755)
39. [Interaction with Smad4 is indispensable for suppression of BMP signaling by c-Ski](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755)
40. [Interaction with Smad4 is indispensable for suppression of BMP signaling by c-Ski](http://www.ebi.ac.uk/QuickGO/annotations?protein=P12755&geneProductId=UniProtKB:P12755)
41. [SKI activates Wnt/beta-catenin signaling in human melanoma](http://www.ebi.ac.uk/QuickGO/annotations?protein=P12755&geneProductId=UniProtKB:P12755)
42. [The protooncogene Ski controls Schwann cell proliferation and myelination](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755)
43. Ensembl Release 99
44. [Identifiers.org](https://registry.identifiers.org/registry/uniprot)