# SIVA1 apoptosis inducing factor

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21131149](https://www.wikidata.org/wiki/Q21131149)  
**Source**: https://4ort.xyz/entity/siva1-apoptosis-inducing-factor-q21131149


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O15304)
3. Q20641742
4. [The zinc containing pro-apoptotic protein siva interacts with the peroxisomal membrane protein pmp22](http://www.ebi.ac.uk/QuickGO/annotations?protein=O15304&geneProductId=UniProtKB:O15304)
5. [Siva-1 binds to and inhibits BCL-X L -mediated protection against UV radiation-induced apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15304)
6. [Human papillomavirus‐16 E7 interacts with siva‐1 and modulates apoptosis in HaCaT human immortalized keratinocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15304)
7. [The Siva-1 putative amphipathic helical region (SAH) is sufficient to bind to BCL-XL and sensitize cells to UV radiation induced apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15304)
8. [CD27, a member of the tumor necrosis factor receptor family, induces apoptosis and binds to Siva, a proapoptotic protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15304)
9. [The zinc containing pro-apoptotic protein siva interacts with the peroxisomal membrane protein pmp22](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15304)
10. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15304)
11. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O15304&geneProductId=UniProtKB:O15304)
12. [The Siva-1 putative amphipathic helical region (SAH) is sufficient to bind to BCL-XL and sensitize cells to UV radiation induced apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?protein=O15304&geneProductId=UniProtKB:O15304)
13. [Siva-1 binds to and inhibits BCL-X L -mediated protection against UV radiation-induced apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?protein=O15304&geneProductId=UniProtKB:O15304)
14. [Siva-1 negatively regulates NF-κB activity: effect on T-cell receptor-mediated activation-induced cell death (AICD)](http://www.ebi.ac.uk/QuickGO/annotations?protein=O15304&geneProductId=UniProtKB:O15304)
15. [Siva-1 and an Alternative Splice Form Lacking the Death Domain, Siva-2, Similarly Induce Apoptosis in T Lymphocytes via a Caspase-Dependent Mitochondrial Pathway](http://www.ebi.ac.uk/QuickGO/annotations?protein=O15304&geneProductId=UniProtKB:O15304)
16. Ensembl Release 99