# Sirtuin 5

> mammalian protein found in Mus musculus

**Wikidata**: [Q21983822](https://www.wikidata.org/wiki/Q21983822)  
**Source**: https://4ort.xyz/entity/sirtuin-5-q21983822


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q8K2C6)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K2C6)
5. [Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K2C6)
6. [The first identification of lysine malonylation substrates and its regulatory enzyme](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K2C6)
7. [SIRT5 regulates the mitochondrial lysine succinylome and metabolic networks](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K2C6)
8. [SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K2C6)
9. [Lysine glutarylation is a protein posttranslational modification regulated by SIRT5](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K2C6)
10. [SIRT5 Deacetylates carbamoyl phosphate synthetase 1 and regulates the urea cycle](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K2C6)
11. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K2C6&geneProductId=UniProtKB:Q8K2C6)
12. [SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K2C6&geneProductId=UniProtKB:Q8K2C6)
13. [Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K2C6&geneProductId=UniProtKB:Q8K2C6)
14. [Nutritional stress exacerbates hepatic steatosis induced by deletion of the histidine nucleotide-binding (Hint2) mitochondrial protein](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K2C6&geneProductId=UniProtKB:Q8K2C6)
15. [A mitochondrial protein compendium elucidates complex I disease biology](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K2C6&geneProductId=UniProtKB:Q8K2C6)
16. [Localization of mouse mitochondrial SIRT proteins: shift of SIRT3 to nucleus by co-expression with SIRT5](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K2C6)
17. [Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K2C6)
18. [Nutritional stress exacerbates hepatic steatosis induced by deletion of the histidine nucleotide-binding (Hint2) mitochondrial protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K2C6)
19. [A mitochondrial protein compendium elucidates complex I disease biology](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K2C6)
20. ensembl Release 106