# Single Ig and TIR domain containing

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21136100](https://www.wikidata.org/wiki/Q21136100)  
**Source**: https://4ort.xyz/entity/single-ig-and-tir-domain-containing


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q6IA17)
3. Q20641742
4. [A novel binding protein of single immunoglobulin IL-1 receptor-related molecule: Paralemmin-3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6IA17)
5. [SIGIRR, a negative regulator of Toll-like receptor-interleukin 1 receptor signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6IA17)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6IA17)
7. [Identification and characterization of SIGIRR, a molecule representing a novel subtype of the IL-1R superfamily](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6IA17)
8. [SIGIRR inhibits interleukin-1 receptor- and toll-like receptor 4-mediated signaling through different mechanisms](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6IA17)
9. Ensembl Release 99