# Signal transducer and activator of transcription 5A

> mammalian protein found in Mus musculus

**Wikidata**: [Q21498877](https://www.wikidata.org/wiki/Q21498877)  
**Source**: https://4ort.xyz/entity/signal-transducer-and-activator-of-transcription-5a


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P42230)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42230)
5. [Effects of hyperactive Janus kinase 2 signaling in mammary epithelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42230)
6. [Caveolin-1-deficient mice show accelerated mammary gland development during pregnancy, premature lactation, and hyperactivation of the Jak-2/STAT5a signaling cascade.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42230)
7. [Stat5 activation is uniquely associated with cytokine signaling in peripheral T cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42230)
8. [CPAP is a novel stat5-interacting cofactor that augments stat5-mediated transcriptional activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42230)
9. [Pecam-1 is a modulator of stat family member phosphorylation and localization: lessons from a transgenic mouse](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42230)
10. [PIKE-A is required for prolactin-mediated STAT5a activation in mammary gland development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42230)
11. [Mammalian protein-protein interaction trap (MAPPIT) analysis of STAT5, CIS, and SOCS2 interactions with the growth hormone receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42230)
12. [Growth hormone promotes the association of transcription factor STAT5 with the growth hormone receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42230)
13. [IL-3-induced enhancement of retinoic acid receptor activity is mediated through Stat5, which physically associates with retinoic acid receptors in an IL-3-dependent manner](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42230)
14. [IL-1 family members and STAT activators induce cytokine production by Th2, Th17, and Th1 cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42230)
15. [Stat5 activation is uniquely associated with cytokine signaling in peripheral T cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42230&geneProductId=UniProtKB:P42230)
16. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42230)
17. [Mammary epithelial cells are not able to undergo pregnancy-dependent differentiation in the absence of the helix-loop-helix inhibitor Id2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42230)
18. [Beta1 integrins regulate chondrocyte rotation, G1 progression, and cytokinesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42230)
19. [Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42230)
20. [Antiapoptotic activity of Stat5 required during terminal stages of myeloid differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42230)
21. [Altered metabolism of growth hormone receptor mutant mice: a combined NMR metabonomics and microarray study](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42230&geneProductId=UniProtKB:P42230)
22. [Epithelial defect in prostates of Stat5a-null mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42230)
23. [Stat5b is essential for natural killer cell-mediated proliferation and cytolytic activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42230)
24. [STAT5 is required for thymopoiesis in a development stage-specific manner](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42230)
25. [Mouse mammary epithelial cells express the Na-K-Cl cotransporter, NKCC1: characterization, localization, and involvement in ductal development and morphogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42230)
26. [ECM1 controls TH2 cell egress from lymph nodes through re-expression of S1P1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42230)
27. [Stat5a/b contribute to interleukin 7-induced B-cell precursor expansion, but abl- and bcr/abl-induced transformation are independent of stat5](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42230)
28. [Regulation of progesterone levels during pregnancy and parturition by signal transducer and activator of transcription 5 and 20alpha-hydroxysteroid dehydrogenase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42230)
29. [JANEX-1, a JAK3 inhibitor, protects pancreatic islets from cytokine toxicity through downregulation of NF-kappaB activation and the JAK/STAT pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42230)
30. [Stat5a is essential for the proliferation and survival of murine mast cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42230)
31. [Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42230)
32. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42230&geneProductId=UniProtKB:P42230)
33. [Signal transducer and activator of transcription (Stat) 5 controls the proliferation and differentiation of mammary alveolar epithelium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42230)
34. [Critical role of AZI2 in GM-CSF-induced dendritic cell differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42230)
35. [Altered metabolism of growth hormone receptor mutant mice: a combined NMR metabonomics and microarray study](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42230)
36. [IL-7-induced phosphorylation of the adaptor Crk-like and other targets](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42230)
37. ensembl Release 106