# Signal transducer and activator of transcription 3

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28563319](https://www.wikidata.org/wiki/Q28563319)  
**Source**: https://4ort.xyz/entity/signal-transducer-and-activator-of-transcription-3-q28563319


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P52631)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631)
5. [Transcription factors Stat3 and Stat5b are present in rat liver nuclei late in an acute phase response and bind interleukin-6 response elements](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631)
6. [ephrinB1 signals from the cell surface to the nucleus by recruitment of STAT3.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631)
7. [SH2B1β Interacts with STAT3 and Enhances Fibroblast Growth Factor 1-Induced Gene Expression during Neuronal Differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631)
8. [Signal regulatory protein alpha ligation induces macrophage nitric oxide production through JAK/STAT- and phosphatidylinositol 3-kinase/Rac1/NAPDH oxidase/H2O2-dependent pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631)
9. [Association of Stat3 with HSF1 plays a critical role in G-CSF-induced cardio-protection against ischemia/reperfusion injury](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631)
10. [In vivo GSH depletion induces c-myc expression by modulation of chromatin protein complexes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631)
11. [Chemokine receptor expression and in vivo signaling pathways in the joints of rats with adjuvant-induced arthritis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631)
12. [Association of the glucocorticoid receptor with STAT3, C/EBPbeta, and the hormone-responsive element within the rat haptoglobin gene promoter during the acute phase response](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631)
13. [Peptide YY attenuates STAT1 and STAT3 activation induced by TNF-alpha in acinar cell line AR42J](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631)
14. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631)
15. [Oxysterol and diabetes activate STAT3 and control endothelial expression of profilin-1 via OSBP1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631)
16. [Nuclear translocation of the transcription factor STAT5 in the rat brain after systemic leptin administration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631)
17. [Change of cardiac mitochondrial STAT3 activity in rats with selenium deficiency and its relation with myocardial injury](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631)
18. [The import of the transcription factor STAT3 into mitochondria depends on GRIM-19, a component of the electron transport chain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631)
19. [Occurrence of a transcription factor, signal transducer and activators of transcription 3 (Stat3), in the postsynaptic density of the rat brain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631)
20. [The Jak/STAT pathway is involved in synaptic plasticity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631)
21. [Age-related alterations in retinal neurovascular and inflammatory transcripts](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631)
22. [Multiple signaling pathways mediate ghrelin-induced proliferation of hippocampal neural stem cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631)
23. [Protective effects of estradiol on ethanol-induced bone loss involve inhibition of reactive oxygen species generation in osteoblasts and downstream activation of the extracellular signal-regulated kinase/signal transducer and activator of [...]](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631)
24. [The STAT3 inhibitor stattic impairs cardiomyocyte mitochondrial function through increased reactive oxygen species formation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631)
25. [Dual activation of STAT-3 and Akt is required during the trigger phase of ischaemic preconditioning](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631)
26. [Prevention of hypovolemic circulatory collapse by IL-6 activated Stat3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631)
27. [Signal transducer and activator of transcription 3-regulated sarcoendoplasmic reticulum Ca2+-ATPase 2 expression by prolactin and glucocorticoids is involved in the adaptation of insulin secretory response during the peripartum period](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631)
28. [TNF-α-sensitive brain pericytes activate microglia by releasing IL-6 through cooperation between IκB-NFκB and JAK-STAT3 pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631)
29. [STAT3 deletion sensitizes cells to oxidative stress](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631)
30. [JANEX-1, a JAK3 inhibitor, protects pancreatic islets from cytokine toxicity through downregulation of NF-kappaB activation and the JAK/STAT pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631)
31. [Survivin Is a transcriptional target of STAT3 critical to estradiol neuroprotection in global ischemia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631)
32. [Interleukin-6-induced satellite cell proliferation is regulated by induction of the JAK2/STAT3 signalling pathway through cyclin D1 targeting](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631)
33. ensembl Release 106