# signal transducer and activator of transcription 2

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21156484](https://www.wikidata.org/wiki/Q21156484)  
**Source**: https://4ort.xyz/entity/signal-transducer-and-activator-of-transcription-2-q21156484


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P52630)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52630)
5. [Phosphorylated interferon-alpha receptor 1 subunit (IFNaR1) acts as a docking site for the latent form of the 113 kDa STAT2 protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52630)
6. [Functional subdomains of STAT2 required for preassociation with the alpha interferon receptor and for signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52630)
7. [Mapping a dynamic innate immunity protein interaction network regulating type I interferon production](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52630)
8. [STAT2 is a primary target for measles virus V protein-mediated alpha/beta interferon signaling inhibition](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52630)
9. [PIPINO: A Software Package to Facilitate the Identification of Protein-Protein Interactions from Affinity Purification Mass Spectrometry Data](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52630)
10. [IFNβ-dependent increases in STAT1, STAT2, and IRF9 mediate resistance to viruses and DNA damage](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52630)
11. [Hepatitis C virus expression suppresses interferon signaling by degrading STAT1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52630)
12. [Affinity of Stat2 for the subunits of the interferon alpha receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52630)
13. [Simian virus 5 V protein acts as an adaptor, linking DDB1 to STAT2, to facilitate the ubiquitination of STAT1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52630)
14. [Acetylation-dependent signal transduction for type I interferon receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52630)
15. [Identification of Amino Acid Residues Critical for the Src-homology 2 Domain-dependent Docking of Stat2 to the Interferon α Receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52630)
16. [The SH2 domains of Stat1 and Stat2 mediate multiple interactions in the transduction of IFN-alpha signals](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52630)
17. [Divergent susceptibilities of human herpesvirus 6 variants to type I interferons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52630)
18. [Global functional profiling of human ubiquitome identifies E3 ubiquitin ligase DCST1 as a novel negative regulator of Type-I interferon signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52630)
19. [A census of human transcription factors: function, expression and evolution](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52630)
20. [Stat2 is a transcriptional activator that requires sequence-specific contacts provided by stat1 and p48 for stable interaction with DNA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P52630&geneProductId=UniProtKB:P52630)
21. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52630)
22. [Stat2 is a transcriptional activator that requires sequence-specific contacts provided by stat1 and p48 for stable interaction with DNA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52630)
23. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P52630&geneProductId=UniProtKB:P52630)
24. [Signal transducer and activator of transcription 2 deficiency is a novel disorder of mitochondrial fission](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52630)
25. [STAT2 deficiency and susceptibility to viral illness in humans](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52630)
26. ensembl Release 95
27. UMLS 2023