# Signal peptide peptidase like 2C

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21122090](https://www.wikidata.org/wiki/Q21122090)  
**Source**: https://4ort.xyz/entity/signal-peptide-peptidase-like-2c


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q8IUH8)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IUH8)
5. [Consensus Analysis of Signal Peptide Peptidase and Homologous Human Aspartic Proteases Reveals Opposite Topology of Catalytic Domains Compared with Presenilins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IUH8)
6. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IUH8)
7. [Consensus Analysis of Signal Peptide Peptidase and Homologous Human Aspartic Proteases Reveals Opposite Topology of Catalytic Domains Compared with Presenilins](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IUH8&geneProductId=UniProtKB:Q8IUH8)
8. [SPPL2a and SPPL2b promote intramembrane proteolysis of TNFα in activated dendritic cells to trigger IL-12 production](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IUH8)
9. [Regulated Intramembrane Proteolysis of Bri2 (Itm2b) by ADAM10 and SPPL2a/SPPL2b](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IUH8)
10. Ensembl Release 99