# Siah E3 ubiquitin protein ligase 2

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21123631](https://www.wikidata.org/wiki/Q21123631)  
**Source**: https://4ort.xyz/entity/siah-e3-ubiquitin-protein-ligase-2-q21123631


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O43255)
3. Q20641742
4. [hSiah2 is a new Vav binding protein which inhibits Vav-mediated signaling pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43255)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43255)
6. [USP13 enzyme regulates Siah2 ligase stability and activity via noncatalytic ubiquitin-binding domains](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43255)
7. [Ubiquitin ligase Siah2 regulates RevErbα degradation and the mammalian circadian clock](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43255)
8. [Hypoxia regulates Hippo signalling through the SIAH2 ubiquitin E3 ligase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43255)
9. [Possible role of death receptor-mediated apoptosis by the E3 ubiquitin ligases Siah2 and POSH](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43255)
10. [MOR Is Not Enough: Identification of Novel mu-Opioid Receptor Interacting Proteins Using Traditional and Modified Membrane Yeast Two-Hybrid Screens](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43255)
11. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O43255&geneProductId=UniProtKB:O43255)
12. [Maturation of human dendritic cells is accompanied by functional remodelling of the ubiquitin-proteasome system](http://www.ebi.ac.uk/QuickGO/annotations?protein=O43255&geneProductId=UniProtKB:O43255)
13. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43255)
14. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=O43255&geneProductId=UniProtKB:O43255)
15. [Wnt-5a inhibits the canonical Wnt pathway by promoting GSK-3-independent beta-catenin degradation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43255)
16. [Mammalian homologs of seven in absentia regulate DCC via the ubiquitin–proteasome pathway](http://www.ebi.ac.uk/QuickGO/annotations?protein=O43255&geneProductId=UniProtKB:O43255)
17. [Mammalian homologs of seven in absentia regulate DCC via the ubiquitin–proteasome pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43255)
18. Ensembl Release 99