# SH3 and multiple ankyrin repeat domains 3

> mammalian protein found in Mus musculus

**Wikidata**: [Q21986777](https://www.wikidata.org/wiki/Q21986777)  
**Source**: https://4ort.xyz/entity/sh3-and-multiple-ankyrin-repeat-domains-3-q21986777


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q4ACU6)
3. Q20641742
4. [The neuronal scaffold protein Shank3 mediates signaling and biological function of the receptor tyrosine kinase Ret in epithelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4ACU6)
5. [Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4ACU6)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4ACU6)
7. [Direct interaction of post-synaptic density-95/Dlg/ZO-1 domain-containing synaptic molecule Shank3 with GluR1 alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q4ACU6&geneProductId=UniProtKB:Q4ACU6)
8. [Direct interaction of GluRdelta2 with Shank scaffold proteins in cerebellar Purkinje cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q4ACU6&geneProductId=UniProtKB:Q4ACU6)
9. [Direct interaction of post-synaptic density-95/Dlg/ZO-1 domain-containing synaptic molecule Shank3 with GluR1 alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4ACU6)
10. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q4ACU6&geneProductId=UniProtKB:Q4ACU6)
11. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4ACU6)
12. [Direct interaction of GluRdelta2 with Shank scaffold proteins in cerebellar Purkinje cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4ACU6)
13. [Altered mGluR5-Homer scaffolds and corticostriatal connectivity in a Shank3 complete knockout model of autism.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4ACU6)
14. [Shank3 mutant mice display autistic-like behaviours and striatal dysfunction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4ACU6)
15. [JAKMIP1, a Novel Regulator of Neuronal Translation, Modulates Synaptic Function and Autistic-like Behaviors in Mouse](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q4ACU6&geneProductId=UniProtKB:Q4ACU6)
16. [Importance of Shank3 protein in regulating metabotropic glutamate receptor 5 (mGluR5) expression and signaling at synapses](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q4ACU6&geneProductId=UniProtKB:Q4ACU6)
17. [Importance of Shank3 protein in regulating metabotropic glutamate receptor 5 (mGluR5) expression and signaling at synapses](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4ACU6)
18. [Synaptic dysfunction and abnormal behaviors in mice lacking major isoforms of Shank3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4ACU6)
19. [Haploinsufficiency of the autism-associated Shank3 gene leads to deficits in synaptic function, social interaction, and social communication](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4ACU6)
20. [Shank3 mutant mice display autistic-like behaviours and striatal dysfunction](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q4ACU6&geneProductId=UniProtKB:Q4ACU6)
21. [The insulin receptor substrate of 53 kDa (IRSp53) limits hippocampal synaptic plasticity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4ACU6)
22. [Synaptic dysfunction and abnormal behaviors in mice lacking major isoforms of Shank3](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q4ACU6&geneProductId=UniProtKB:Q4ACU6)
23. [Haploinsufficiency of the autism-associated Shank3 gene leads to deficits in synaptic function, social interaction, and social communication](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q4ACU6&geneProductId=UniProtKB:Q4ACU6)
24. ensembl Release 106