# Sex lethal Dmel_CG43770

> protein found in Drosophila melanogaster

**Wikidata**: [Q29819663](https://www.wikidata.org/wiki/Q29819663)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/Sex-lethal)  
**Source**: https://4ort.xyz/entity/sex-lethal-dmel-cg43770


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P19339)
3. Q20641742
4. [Translational repressors in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19339)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19339)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P19339&geneProductId=UniProtKB:P19339)
7. [Sex determination in flies, fruitflies and butterflies](http://www.ebi.ac.uk/QuickGO/annotations?protein=P19339&geneProductId=UniProtKB:P19339)
8. [The drosophila melanogaster genome: translation factors and RNA binding proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=P19339&geneProductId=UniProtKB:P19339)
9. [A dual inhibitory mechanism restricts msl-2 mRNA translation for dosage compensation in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?protein=P19339&geneProductId=UniProtKB:P19339)
10. [A positive role for Patched in Hedgehog signaling revealed by the intracellular trafficking of Sex-lethal, the Drosophila sex determination master switch](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19339)
11. [Glorund interactions in the regulation of gurken and oskar mRNAs](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19339)
12. [The sex determination master switch, Sex-lethal, responds to Hedgehog signaling in the Drosophila germline](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19339)
13. [SIN, a novel Drosophila protein that associates with the RNA binding protein sex-lethal](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19339)
14. [A large complex containing Patched and Smoothened initiates Hedgehog signaling in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19339)
15. [Inhibition of msl-2 splicing by Sex-lethal reveals interaction between U2AF35 and the 3' splice site AG.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19339)
16. [Differential recognition of the polypyrimidine-tract by the general splicing factor U2AF65 and the splicing repressor sex-lethal](http://www.ebi.ac.uk/QuickGO/annotations?protein=P19339&geneProductId=UniProtKB:P19339)
17. [The m6A pathway facilitates sex determination in Drosophila.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19339)
18. [Translational repressors in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?protein=P19339&geneProductId=UniProtKB:P19339)
19. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19339)
20. [A dual inhibitory mechanism restricts msl-2 mRNA translation for dosage compensation in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19339)
21. [Differential recognition of the polypyrimidine-tract by the general splicing factor U2AF65 and the splicing repressor sex-lethal](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19339)
22. [Sex-lethal enables germline stem cell differentiation by down-regulating Nanos protein levels during Drosophila oogenesis.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P19339&geneProductId=UniProtKB:P19339)
23. [Sex-lethal enables germline stem cell differentiation by down-regulating Nanos protein levels during Drosophila oogenesis.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19339)
24. [Biochemical function of female-lethal (2)D/Wilms' tumor suppressor-1-associated proteins in alternative pre-mRNA splicing.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P19339&geneProductId=UniProtKB:P19339)
25. [Structure and novel functional mechanism of Drosophila SNF in sex-lethal splicing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19339)
26. [Structure, function and evolution of sex-determining systems in Dipteran insects](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19339)
27. [Splitting the Hedgehog signal: sex and patterning in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?protein=P19339&geneProductId=UniProtKB:P19339)
28. [Splitting the Hedgehog signal: sex and patterning in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19339)
29. [Sex-determination gene and pathway evolution in nematodes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P19339&geneProductId=UniProtKB:P19339)
30. [The dice of fate: the csd gene and how its allelic composition regulates sexual development in the honey bee, Apis mellifera](http://www.ebi.ac.uk/QuickGO/annotations?protein=P19339&geneProductId=UniProtKB:P19339)
31. [Evolutionary consequences of Wolbachia infections](http://www.ebi.ac.uk/QuickGO/annotations?protein=P19339&geneProductId=UniProtKB:P19339)
32. [Runt and Lozenge function in Drosophila development](http://www.ebi.ac.uk/QuickGO/annotations?protein=P19339&geneProductId=UniProtKB:P19339)
33. [Courtship in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?protein=P19339&geneProductId=UniProtKB:P19339)
34. [Sex comes in from the cold: the integration of sex and pattern](http://www.ebi.ac.uk/QuickGO/annotations?protein=P19339&geneProductId=UniProtKB:P19339)
35. [Are complex behaviors specified by dedicated regulatory genes? Reasoning from Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?protein=P19339&geneProductId=UniProtKB:P19339)
36. [Germ cell development in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?protein=P19339&geneProductId=UniProtKB:P19339)
37. [deadpan, an essential pan-neural gene encoding an HLH protein, acts as a denominator in Drosophila sex determination](http://www.ebi.ac.uk/QuickGO/annotations?protein=P19339&geneProductId=UniProtKB:P19339)
38. [Structure, function and evolution of sex-determining systems in Dipteran insects](http://www.ebi.ac.uk/QuickGO/annotations?protein=P19339&geneProductId=UniProtKB:P19339)
39. [Sex-lethal is a target of Bruno-mediated translational repression in promoting the differentiation of stem cell progeny during Drosophila oogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19339)
40. [Masters change, slaves remain](http://www.ebi.ac.uk/QuickGO/annotations?protein=P19339&geneProductId=UniProtKB:P19339)
41. [Establishing sexual dimorphism: conservation amidst diversity?](http://www.ebi.ac.uk/QuickGO/annotations?protein=P19339&geneProductId=UniProtKB:P19339)
42. [Sex-lethal imparts a sex-specific function to UNR by recruiting it to the msl-2 mRNA 3' UTR: translational repression for dosage compensation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P19339&geneProductId=UniProtKB:P19339)
43. [The m6A pathway facilitates sex determination in Drosophila.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P19339&geneProductId=UniProtKB:P19339)
44. [deadpan, an essential pan-neural gene encoding an HLH protein, acts as a denominator in Drosophila sex determination](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19339)
45. [The sexual identity of adult intestinal stem cells controls organ size and plasticity.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19339)
46. [The dice of fate: the csd gene and how its allelic composition regulates sexual development in the honey bee, Apis mellifera](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19339)
47. [Sex-determination gene and pathway evolution in nematodes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19339)
48. [Runt and Lozenge function in Drosophila development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19339)
49. [Evolutionary consequences of Wolbachia infections](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19339)
50. [Sex comes in from the cold: the integration of sex and pattern](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19339)