# Sex determining region Y

> mammalian protein found in Homo sapiens

**Wikidata**: [Q409114](https://www.wikidata.org/wiki/Q409114)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/Sex-determining_region_Y_protein)  
**Source**: https://4ort.xyz/entity/sex-determining-region-y


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q05066)
3. Q20641742
4. Freebase Data Dumps. 2013
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05066)
6. [The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05066)
7. [Failure of SOX9 Regulation in 46XY Disorders of Sex Development with SRY, SOX9 and SF1 Mutations](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05066&geneProductId=UniProtKB:Q05066)
8. [SRY, like HMG1, recognizes sharp angles in DNA.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05066)
9. [The SRY high-mobility-group box recognizes DNA by partial intercalation in the minor groove: a topological mechanism of sequence specificity.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05066)
10. [A census of human transcription factors: function, expression and evolution](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05066&geneProductId=UniProtKB:Q05066)
11. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05066&geneProductId=UniProtKB:Q05066)
12. [Proteomics‐based identification of proteins interacting with Smad3: SREBP‐2 forms a complex with Smad3 and inhibits its transcriptional activity](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05066&geneProductId=UniProtKB:Q05066)
13. [NHERF2/SIP-1 interacts with mouse SRY via a different mechanism than human SRY.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05066&geneProductId=UniProtKB:Q05066)
14. [The human testis determining factor SRY binds a nuclear factor containing PDZ protein interaction domains](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05066&geneProductId=UniProtKB:Q05066)
15. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05066&geneProductId=UniProtKB:Q05066)
16. [A census of human transcription factors: function, expression and evolution](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05066)
17. [Failure of SOX9 Regulation in 46XY Disorders of Sex Development with SRY, SOX9 and SF1 Mutations](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05066)
18. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05066)
19. [The SRY high-mobility-group box recognizes DNA by partial intercalation in the minor groove: a topological mechanism of sequence specificity.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05066&geneProductId=UniProtKB:Q05066)
20. [SRY, like HMG1, recognizes sharp angles in DNA.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05066&geneProductId=UniProtKB:Q05066)
21. [A Novel Missense Mutation 224G>T (R75M) in SRY Coding Region Interferes with Nuclear Import and Results in 46, XY Complete Gonadal Dysgenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05066&geneProductId=UniProtKB:Q05066)
22. [A Novel Missense Mutation 224G>T (R75M) in SRY Coding Region Interferes with Nuclear Import and Results in 46, XY Complete Gonadal Dysgenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05066)
23. [A gene from the human sex-determining region encodes a protein with homology to a conserved DNA-binding motif](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05066&geneProductId=UniProtKB:Q05066)
24. [A gene from the human sex-determining region encodes a protein with homology to a conserved DNA-binding motif](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05066)
25. [The NLR-related protein NWD1 is associated with prostate cancer and modulates androgen receptor signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05066)
26. Ensembl Release 99
27. Identifiers.org
28. UMLS 2023
29. [OpenAlex](https://docs.openalex.org/download-snapshot/snapshot-data-format)