# SET domain containing 2, histone lysine methyltransferase

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21118252](https://www.wikidata.org/wiki/Q21118252)  
**Source**: https://4ort.xyz/entity/set-domain-containing-2-histone-lysine-methyltransferase


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q9BYW2)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BYW2)
5. [Methyltransferase SETD2-Mediated Methylation of STAT1 Is Critical for Interferon Antiviral Activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BYW2)
6. [The Iws1:Spt6:CTD complex controls cotranscriptional mRNA biosynthesis and HYPB/Setd2-mediated histone H3K36 methylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BYW2)
7. [Huntingtin interacting proteins are genetic modifiers of neurodegeneration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BYW2)
8. [Toward an understanding of the protein interaction network of the human liver](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BYW2)
9. [The histone mark H3K36me3 regulates human DNA mismatch repair through its interaction with MutSα](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BYW2)
10. [Sinefungin derivatives as inhibitors and structure probes of protein lysine methyltransferase SETD2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BYW2)
11. [Dual Chromatin and Cytoskeletal Remodeling by SETD2.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BYW2)
12. [Molecular basis for oncohistone H3 recognition by SETD2 methyltransferase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BYW2)
13. [SETD2 is required for DNA double-strand break repair and activation of the p53-mediated checkpoint.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BYW2)
14. [Kinetic characterization of human histone H3 lysine 36 methyltransferases, ASH1L and SETD2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BYW2)
15. [Histone methyltransferase SETD2 coordinates FACT recruitment with nucleosome dynamics during transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BYW2)
16. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BYW2&geneProductId=UniProtKB:Q9BYW2)
17. Ensembl Release 99
18. UMLS 2023