SET domain containing 1A
type: Thing
description: mammalian protein found in Mus musculus
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P352
  value: E9PYH6
additional property: PropertyValue
  property ID: P361
  value: Nucleotide-binding alpha-beta plait domain superfamily
additional property: PropertyValue
  property ID: P361
  value: RNA-binding domain superfamily
additional property: PropertyValue
  property ID: P361
  value: Histone-lysine N-methyltransferase SETD1A
additional property: PropertyValue
  property ID: P527
  value: COMPASS complex Set1 subunit, N-SET domain
additional property: PropertyValue
  property ID: P527
  value: RNA recognition motif domain
additional property: PropertyValue
  property ID: P527
  value: Set1A, RNA recognition motif
additional property: PropertyValue
  property ID: P637
  value: NP_821172
additional property: PropertyValue
  property ID: P680
  value: nucleic acid binding
additional property: PropertyValue
  property ID: P680
  value: RNA binding
additional property: PropertyValue
  property ID: P680
  value: protein binding
additional property: PropertyValue
  property ID: P681
  value: nucleus
additional property: PropertyValue
  property ID: P681
  value: chromosome
additional property: PropertyValue
  property ID: P681
  value: nuclear speck
additional property: PropertyValue
  property ID: P682
  value: chromatin organization
additional property: PropertyValue
  property ID: P682
  value: positive regulation of gene expression
additional property: PropertyValue
  property ID: P682
  value: stem cell population maintenance
additional property: PropertyValue
  property ID: P702
  value: Setd1a
additional property: PropertyValue
  property ID: P703
  value: house mouse
additional property: PropertyValue
  property ID: P705
  value: ENSMUSP00000120666
additional property: PropertyValue
  property ID: P705
  value: ENSMUSP00000047672
additional property: PropertyValue
  property ID: P705
  value: ENSMUSP00000115994
confidence:
  popularity graph score:
    score: 0.001
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 10
      unique citations norm: 0.004
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 10
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: E9PYH6
    source count: 1
    confidence: 0.2
  P361:
    value: Q54450559
    source count: 1
    confidence: 0.2
    value label: Nucleotide-binding alpha-beta plait domain superfamily
  P361:
    value: Q41797127
    source count: 1
    confidence: 0.2
    value label: RNA-binding domain superfamily
  P361:
    value: Q54442005
    source count: 1
    confidence: 0.2
    value label: Histone-lysine N-methyltransferase SETD1A
  P361:
    value: Q83165382
    source count: 1
    confidence: 0.2
    value label: COMPASS complex Set1 subunit, N-SET domain, protein family
  P361:
    value: Q83140138
    source count: 1
    confidence: 0.2
    value label: Post-SET domain, protein family
  P527:
    value: Q24785950
    source count: 1
    confidence: 0.2
    value label: COMPASS complex Set1 subunit, N-SET domain
  P527:
    value: Q24768845
    source count: 1
    confidence: 0.2
    value label: RNA recognition motif domain
  P527:
    value: Q29564638
    source count: 1
    confidence: 0.2
    value label: Set1A, RNA recognition motif
  P527:
    value: Q24770698
    source count: 1
    confidence: 0.2
    value label: Post-SET domain
  P527:
    value: Q24770667
    source count: 1
    confidence: 0.2
    value label: SET domain
  P637:
    value: NP_821172
    source count: 1
    confidence: 0.2
  P680:
    value: Q14864825
    source count: 1
    confidence: 0.2
    value label: nucleic acid binding
  P680:
    value: Q14330639
    source count: 1
    confidence: 0.2
    value label: RNA binding
  P680:
    value: Q167149
    source count: 1
    confidence: 0.2
    value label: protein binding
  P680:
    value: Q14872998
    source count: 1
    confidence: 0.2
    value label: beta-catenin binding
  P680:
    value: Q14817982
    source count: 1
    confidence: 0.2
    value label: transcription factor binding
  P681:
    value: Q40260
    source count: 3
    confidence: 0.6
    value label: nucleus
  P681:
    value: Q37748
    source count: 1
    confidence: 0.2
    value label: chromosome
  P681:
    value: Q14819271
    source count: 2
    confidence: 0.4
    value label: nuclear speck
  P681:
    value: Q14913027
    source count: 2
    confidence: 0.4
    value label: histone methyltransferase complex
  P681:
    value: Q21102076
    source count: 3
    confidence: 0.6
    value label: Set1C/COMPASS complex

value: Q15322272
source count: 1
confidence: 0.2
value label: chromatin organization

value: Q14633893
source count: 1
confidence: 0.2
value label: positive regulation of gene expression

value: Q14864669
source count: 1
confidence: 0.2
value label: stem cell population maintenance

value: Q518328
source count: 1
confidence: 0.2
value label: methylation

value: Q14911761
source count: 1
confidence: 0.2
value label: regulation of erythrocyte differentiation

value: Q18298279
source count: 1
confidence: 0.2
value label: Setd1a

value: Q83310
source count: 1
confidence: 0.2
value label: house mouse

value: ENSMUSP00000120666
source count: 1
confidence: 0.2

value: ENSMUSP00000047672
source count: 1
confidence: 0.2

value: ENSMUSP00000115994
source count: 1
confidence: 0.2

value: ENSMUSP00000115248
source count: 1
confidence: 0.2

value: ENSMUSP00000037600
source count: 1
confidence: 0.2

source: GOA
stated in qid: Q28018111
retrieved: 2019-02-14

source: Nap1l1 Controls Embryonic Neural Progenitor Cell Proliferation and Differentiation in the Developing Brain
stated in qid: Q52430535
retrieved: 2019-02-14

source: Wnt/β-catenin signaling regulates telomerase in stem cells and cancer cells
stated in qid: Q24338743
retrieved: 2019-02-14

source: Setd1a and NURF mediate chromatin dynamics and gene regulation during erythroid lineage commitment and differentiation
stated in qid: Q28117414
retrieved: 2019-02-14

source: PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex
stated in qid: Q24305512
retrieved: 2019-02-14

source: The H3K4 methyltransferase Setd1a is first required at the epiblast stage, whereas Setd1b becomes essential after gastrulation
stated in qid: Q28585543
retrieved: 2019-02-14

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2022-05-25

source: Q20641742
stated in qid: Q20641742
retrieved: 2022-03-20

source: ensembl Release 106
stated in qid: Q111699881

wikidata id: Q57590241
domain: protein
level: standard
html url: https://4ort.xyz/entity/set-domain-containing-1a
markdown url: https://4ort.xyz/entity/set-domain-containing-1a.md
facts url summary: https://4ort.xyz/entity/set-domain-containing-1a/facts.json
facts url standard: https://4ort.xyz/entity/set-domain-containing-1a/facts.json
facts url full: https://4ort.xyz/entity/set-domain-containing-1a/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-23T12:08:52.321150Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T13:49:34.721580+00:00Z