# SET domain containing 1A, histone lysine methyltransferase

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21115985](https://www.wikidata.org/wiki/Q21115985)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/SETD1A)  
**Source**: https://4ort.xyz/entity/set-domain-containing-1a-histone-lysine-methyltransferase


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O15047)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15047)
5. [Wnt/β-catenin signaling regulates telomerase in stem cells and cancer cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15047)
6. [Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15047)
7. [The histone chaperone Spt6 is required for activation-induced cytidine deaminase target determination through H3K4me3 regulation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15047)
8. [PHF8 mediates histone H4 lysine 20 demethylation events involved in cell cycle progression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15047)
9. [BAT3 and SET1A form a complex with CTCFL/BORIS to modulate H3K4 histone dimethylation and gene expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15047)
10. [Wdr82 is a C-terminal domain-binding protein that recruits the Setd1A Histone H3-Lys4 methyltransferase complex to transcription start sites of transcribed human genes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15047)
11. [Structural basis for activity regulation of MLL family methyltransferases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15047)
12. [SET1 and p300 act synergistically, through coupled histone modifications, in transcriptional activation by p53](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15047)
13. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O15047&geneProductId=UniProtKB:O15047)
14. [Setd1a and NURF mediate chromatin dynamics and gene regulation during erythroid lineage commitment and differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15047)
15. [Contribution of H3K4 methylation by SET‐1A to interleukin‐1–induced cyclooxygenase 2 and inducible nitric oxide synthase expression in human osteoarthritis chondrocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15047)
16. [PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15047)
17. [Identification and characterization of the human Set1B histone H3-Lys4 methyltransferase complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15047)
18. [Molecular regulation of H3K4 trimethylation by Wdr82, a component of human Set1/COMPASS](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15047)
19. [Setd1a and NURF mediate chromatin dynamics and gene regulation during erythroid lineage commitment and differentiation](http://www.ebi.ac.uk/QuickGO/annotations?protein=O15047&geneProductId=UniProtKB:O15047)
20. Ensembl Release 99