# Serum response factor

> mammalian protein found in Mus musculus

**Wikidata**: [Q21990643](https://www.wikidata.org/wiki/Q21990643)  
**Source**: https://4ort.xyz/entity/serum-response-factor-q21990643


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q9JM73)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73)
5. [Rho-actin signaling to the MRTF coactivators dominates the immediate transcriptional response to serum in fibroblasts](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73)
6. [Actin dynamics control SRF activity by regulation of its coactivator MAL](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73)
7. [Activation of the cardiac alpha-actin promoter depends upon serum response factor, Tinman homologue, Nkx-2.5, and intact serum response elements](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73)
8. [Myocardin-related transcription factors regulate the Cdk5/Pctaire1 kinase cascade to control neurite outgrowth, neuronal migration and brain development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73)
9. [Loss of phosphatidylinositol 3-phosphate binding by the C-terminal Tiam-1 pleckstrin homology domain prevents in vivo Rac1 activation without affecting membrane targeting](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73)
10. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JM73&geneProductId=UniProtKB:Q9JM73)
11. [Protein Tyrosine Phosphatase-Like A Regulates Myoblast Proliferation and Differentiation through MyoG and the Cell Cycling Signaling Pathway](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JM73&geneProductId=UniProtKB:Q9JM73)
12. [SMYD1, the myogenic activator, is a direct target of serum response factor and myogenin](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JM73&geneProductId=UniProtKB:Q9JM73)
13. [Protein Tyrosine Phosphatase-Like A Regulates Myoblast Proliferation and Differentiation through MyoG and the Cell Cycling Signaling Pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73)
14. [Activation of cardiac gene expression by myocardin, a transcriptional cofactor for serum response factor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73)
15. [SMYD1, the myogenic activator, is a direct target of serum response factor and myogenin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73)
16. [Regulation of cardiac microRNAs by serum response factor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73)
17. [Promoter function and structure of the growth factor-inducible immediate early gene cyr61](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73)
18. [The Cardiac Transcription Network Modulated by Gata4, Mef2a, Nkx2.5, Srf, Histone Modifications, and MicroRNAs](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73)
19. [SCAI acts as a suppressor of cancer cell invasion through the transcriptional control of beta1-integrin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73)
20. [Potentiation of serum response factor activity by a family of myocardin-related transcription factors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73)
21. [Identification of Barx2b, a serum response factor-associated homeodomain protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73)
22. [Pitx2 is functionally important in the early stages of vascular smooth muscle cell differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73)
23. [The SWI/SNF chromatin remodeling complex regulates myocardin-induced smooth muscle-specific gene expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73)
24. [UTX, a Histone H3-Lysine 27 Demethylase, Acts as a Critical Switch to Activate the Cardiac Developmental Program](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73)
25. [UTX and UTY demonstrate histone demethylase-independent function in mouse embryonic development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73)
26. [DeltaEF1 mediates TGF-beta signaling in vascular smooth muscle cell differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73)
27. [Thymine DNA glycosylase represses myocardin-induced smooth muscle cell differentiation by competing with serum response factor for myocardin binding](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73)
28. [Bioinformatics and cellular signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73)
29. [The essential function for serum response factor in T-cell development reflects its specific coupling to extracellular signal-regulated kinase signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73)
30. [The homeodomain protein Barx2 promotes myogenic differentiation and is regulated by myogenic regulatory factors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73)
31. [Bone morphogenetic protein-induced MSX1 and MSX2 inhibit myocardin-dependent smooth muscle gene transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73)
32. [Activation of cardiac gene expression by myocardin, a transcriptional cofactor for serum response factor](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JM73&geneProductId=UniProtKB:Q9JM73)
33. [The Cardiac Transcription Network Modulated by Gata4, Mef2a, Nkx2.5, Srf, Histone Modifications, and MicroRNAs](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JM73&geneProductId=UniProtKB:Q9JM73)
34. [Myocardin-related transcription factors regulate the Cdk5/Pctaire1 kinase cascade to control neurite outgrowth, neuronal migration and brain development](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JM73&geneProductId=UniProtKB:Q9JM73)
35. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JM73&geneProductId=UniProtKB:Q9JM73)
36. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73)
37. [HOP/NECC1, a novel regulator of mouse trophoblast differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73)
38. [Conditional mutagenesis of the murine serum response factor gene blocks cardiogenesis and the transcription of downstream gene targets](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JM73&geneProductId=UniProtKB:Q9JM73)
39. [HOP/NECC1, a novel regulator of mouse trophoblast differentiation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JM73&geneProductId=UniProtKB:Q9JM73)
40. [Loss of phosphatidylinositol 3-phosphate binding by the C-terminal Tiam-1 pleckstrin homology domain prevents in vivo Rac1 activation without affecting membrane targeting](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JM73&geneProductId=UniProtKB:Q9JM73)
41. [Conditional mutagenesis of the murine serum response factor gene blocks cardiogenesis and the transcription of downstream gene targets](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73)
42. [Restricted inactivation of serum response factor to the cardiovascular system](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73)
43. [Establishment of smooth muscle and cartilage juxtaposition in the developing mouse upper airways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73)
44. [Requirement for serum response factor for skeletal muscle growth and maturation revealed by tissue-specific gene deletion in mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73)
45. [Serum response factor is essential for the proper development of skin epithelium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73)
46. [Serum response factor is required for sprouting angiogenesis and vascular integrity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73)
47. [Serum response factor is an essential transcription factor in megakaryocytic maturation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73)
48. [Mouse and human phenotypes indicate a critical conserved role for ERK2 signaling in neural crest development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73)
49. [A role in learning for SRF: deletion in the adult forebrain disrupts LTD and the formation of an immediate memory of a novel context](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73)
50. [A nuclear actin function regulates neuronal motility by serum response factor-dependent gene transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73)