Serine/threonine/tyrosine protein kinase RAD53 YPL153C
fungal protein found in Saccharomyces cerevisiae S288c
serine/threonine-protein kinase, active site
protein serine/threonine/tyrosine kinase activity
Forkhead-associated (FHA) domain, protein family
The Yeast DNA Damage Checkpoint Kinase Rad53 Targets the Exoribonuclease, Xrn1
SPK1 is an essential S-phase-specific gene of Saccharomyces cerevisiae that encodes a nuclear serine/threonine/tyrosine kinase.
Novel role for checkpoint Rad53 protein kinase in the initiation of chromosomal DNA replication in Saccharomyces cerevisiae
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Mdt1, a novel Rad53 FHA1 domain-interacting protein, modulates DNA damage tolerance and G(2)/M cell cycle progression in Saccharomyces cerevisiae.
CDC5 inhibits the hyperphosphorylation of the checkpoint kinase Rad53, leading to checkpoint adaptation
The Saccharomyces cerevisiae 14-3-3 proteins Bmh1 and Bmh2 directly influence the DNA damage-dependent functions of Rad53.
Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry
A novel, evolutionarily conserved protein phosphatase complex involved in cisplatin sensitivity
Defining the budding yeast chromatin‐associated interactome
Checkpoint-dependent inhibition of DNA replication initiation by Sld3 and Dbf4 phosphorylation
Pph3-Psy2 is a phosphatase complex required for Rad53 dephosphorylation and replication fork restart during recovery from DNA damage.
Proteome survey reveals modularity of the yeast cell machinery
A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae
Functional organization of the yeast proteome by systematic analysis of protein complexes
An N-terminal acidic region of Sgs1 interacts with Rpa70 and recruits Rad53 kinase to stalled forks
Uncoupling of unwinding from DNA synthesis implies regulation of MCM helicase by Tof1/Mrc1/Csm3 checkpoint complex.
DNA damage signalling targets the kinetochore to promote chromatin mobility
Rad53 FHA Domain Associated with Phosphorylated Rad9 in the DNA Damage Checkpoint
Damage-induced phosphorylation of Sld3 is important to block late origin firing
Global analysis of protein phosphorylation in yeast
The nuclear localization of SWI/SNF proteins is subjected to oxygen regulation
Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair
Impaired tRNA nuclear export links DNA damage and cell-cycle checkpoint
Inhibition of the mitotic exit network in response to damaged telomeres.
Recovery from DNA replicational stress is the essential function of the S-phase checkpoint pathway