# Serine/threonine kinase 25

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21109159](https://www.wikidata.org/wiki/Q21109159)  
**Source**: https://4ort.xyz/entity/serine-threonine-kinase-25


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O00506)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506)
5. [YSK1, a novel mammalian protein kinase structurally related to Ste20 and SPS1, but is not involved in the known MAPK pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506)
6. [YSK1 is activated by the Golgi matrix protein GM130 and plays a role in cell migration through its substrate 14-3-3ζ](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506)
7. [PDCD10 interacts with STK25 to accelerate cell apoptosis under oxidative stress](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506)
8. [CCM3/PDCD10 stabilizes GCKIII proteins to promote Golgi assembly and cell orientation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506)
9. [CCM3/PDCD10 Heterodimerizes with Germinal Center Kinase III (GCKIII) Proteins Using a Mechanism Analogous to CCM3 Homodimerization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506)
10. [A PP2A Phosphatase High Density Interaction Network Identifies a Novel Striatin-interacting Phosphatase and Kinase Complex Linked to the Cerebral Cavernous Malformation 3 (CCM3) Protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506)
11. [Structural Basis for the Unique Heterodimeric Assembly between Cerebral Cavernous Malformation 3 and Germinal Center Kinase III](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506)
12. [MO25 is a master regulator of SPAK/OSR1 and MST3/MST4/YSK1 protein kinases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506)
13. [Next-generation sequencing to generate interactome datasets](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506)
14. [Towards a proteome-scale map of the human protein–protein interaction network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506)
15. [A Proteome-Scale Map of the Human Interactome Network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506)
16. [Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506)
17. [CCM3 interacts with CCM2 indicating common pathogenesis for cerebral cavernous malformations](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506)
18. [Pooled‐matrix protein interaction screens using Barcode Fusion Genetics](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506)
19. [Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506)
20. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O00506&geneProductId=UniProtKB:O00506)
21. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506)
22. [PDCD10 interacts with STK25 to accelerate cell apoptosis under oxidative stress](http://www.ebi.ac.uk/QuickGO/annotations?protein=O00506&geneProductId=UniProtKB:O00506)
23. [In‐depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=O00506&geneProductId=UniProtKB:O00506)
24. [In‐depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506)
25. [Activation of a human Ste20-like kinase by oxidant stress defines a novel stress response pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506)
26. [Adaptor Protein Cerebral Cavernous Malformation 3 (CCM3) Mediates Phosphorylation of the Cytoskeletal Proteins Ezrin/Radixin/Moesin by Mammalian Ste20-4 to Protect Cells from Oxidative Stress](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506)
27. Ensembl Release 99
28. [Identifiers.org](https://registry.identifiers.org/registry/uniprot)