# Serine palmitoyltransferase, long chain base subunit 1

> mammalian protein found in Mus musculus

**Wikidata**: [Q21988152](https://www.wikidata.org/wiki/Q21988152)  
**Source**: https://4ort.xyz/entity/serine-palmitoyltransferase-long-chain-base-subunit-1-q21988152


## References

1. UniProt
2. IUPHAR/BPS Guide to PHARMACOLOGY
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O35704)
4. Q20641742
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35704)
6. [Nogo-B regulates endothelial sphingolipid homeostasis to control vascular function and blood pressure](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35704)
7. [SPTLC1 binds ABCA1 to negatively regulate trafficking and cholesterol efflux activity of the transporter](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35704)
8. [ORMDL/serine palmitoyltransferase stoichiometry determines effects of ORMDL3 expression on sphingolipid biosynthesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=O35704&geneProductId=UniProtKB:O35704)
9. [Human and murine serine-palmitoyl-CoA transferase--cloning, expression and characterization of the key enzyme in sphingolipid synthesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=O35704&geneProductId=UniProtKB:O35704)
10. [ORMDL/serine palmitoyltransferase stoichiometry determines effects of ORMDL3 expression on sphingolipid biosynthesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35704)
11. [De Novo Sphingolipid Biosynthesis Is Required for Adipocyte Survival and Metabolic Homeostasis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35704)
12. [Human and murine serine-palmitoyl-CoA transferase--cloning, expression and characterization of the key enzyme in sphingolipid synthesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35704)
13. [A Mammalian Homolog of the Yeast LCB1 Encodes a Component of Serine Palmitoyltransferase, the Enzyme Catalyzing the First Step in Sphingolipid Synthesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35704)
14. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O35704&geneProductId=UniProtKB:O35704)
15. [Serine palmitoyl-CoA transferase (SPT) deficiency and sphingolipid levels in mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35704)
16. [A Mammalian Homolog of the Yeast LCB1 Encodes a Component of Serine Palmitoyltransferase, the Enzyme Catalyzing the First Step in Sphingolipid Synthesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=O35704&geneProductId=UniProtKB:O35704)
17. [Serine palmitoyl-CoA transferase (SPT) deficiency and sphingolipid levels in mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=O35704&geneProductId=UniProtKB:O35704)
18. [Serine palmitoyltransferase (SPT) deficient mice absorb less cholesterol](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35704)
19. ensembl Release 106