# Serine hydroxymethyltransferase 2

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21106465](https://www.wikidata.org/wiki/Q21106465)  
**Source**: https://4ort.xyz/entity/serine-hydroxymethyltransferase-2


## References

1. UniProt
2. Q20641742
3. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34897)
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P34897&geneProductId=UniProtKB:P34897)
5. [The layered structure of human mitochondrial DNA nucleoids](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34897)
6. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34897)
7. [Autism and Intellectual Disability-Associated KIRREL3 Interacts with Neuronal Proteins MAP1B and MYO16 with Potential Roles in Neurodevelopment](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34897)
8. [Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34897)
9. [How pyridoxal 5'-phosphate differentially regulates human cytosolic and mitochondrial serine hydroxymethyltransferase oligomeric state](http://www.ebi.ac.uk/QuickGO/annotations?protein=P34897&geneProductId=UniProtKB:P34897)
10. [Cloning of human cDNAs encoding mitochondrial and cytosolic serine hydroxymethyltransferases and chromosomal localization](http://www.ebi.ac.uk/QuickGO/annotations?protein=P34897&geneProductId=UniProtKB:P34897)
11. [A BRISC-SHMT Complex Deubiquitinates IFNAR1 and Regulates Interferon Responses](http://www.ebi.ac.uk/QuickGO/annotations?protein=P34897&geneProductId=UniProtKB:P34897)
12. [Effect of vitamin B6 availability on serine hydroxymethyltransferase in MCF-7 cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P34897&geneProductId=UniProtKB:P34897)
13. [Mitochondrial translation requires folate-dependent tRNA methylation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P34897&geneProductId=UniProtKB:P34897)
14. [SHMT2 Desuccinylation by SIRT5 Drives Cancer Cell Proliferation.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P34897&geneProductId=UniProtKB:P34897)
15. [Serine Catabolism by SHMT2 Is Required for Proper Mitochondrial Translation Initiation and Maintenance of Formylmethionyl-tRNAs](http://www.ebi.ac.uk/QuickGO/annotations?protein=P34897&geneProductId=UniProtKB:P34897)
16. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=P34897&geneProductId=UniProtKB:P34897)
17. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34897)
18. [How pyridoxal 5'-phosphate differentially regulates human cytosolic and mitochondrial serine hydroxymethyltransferase oligomeric state](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34897)
19. [Effect of vitamin B6 availability on serine hydroxymethyltransferase in MCF-7 cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34897)
20. [Cloning of human cDNAs encoding mitochondrial and cytosolic serine hydroxymethyltransferases and chromosomal localization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34897)
21. [SHMT2 Desuccinylation by SIRT5 Drives Cancer Cell Proliferation.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34897)
22. [Mitochondrial translation requires folate-dependent tRNA methylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34897)
23. [Serine Catabolism by SHMT2 Is Required for Proper Mitochondrial Translation Initiation and Maintenance of Formylmethionyl-tRNAs](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34897)
24. [A BRISC-SHMT Complex Deubiquitinates IFNAR1 and Regulates Interferon Responses](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34897)
25. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P34897&geneProductId=UniProtKB:P34897)
26. [MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P34897&geneProductId=UniProtKB:P34897)
27. [Identification of a de novo thymidylate biosynthesis pathway in mammalian mitochondria](http://www.ebi.ac.uk/QuickGO/annotations?protein=P34897&geneProductId=UniProtKB:P34897)
28. [SHMT1 and SHMT2 are functionally redundant in nuclear de novo thymidylate biosynthesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P34897&geneProductId=UniProtKB:P34897)
29. [The role of serine hydroxymethyltransferase isozymes in one-carbon metabolism in MCF-7 cells as determined by (13)C NMR](http://www.ebi.ac.uk/QuickGO/annotations?protein=P34897&geneProductId=UniProtKB:P34897)
30. [Identification of a de novo thymidylate biosynthesis pathway in mammalian mitochondria](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34897)
31. [The role of serine hydroxymethyltransferase isozymes in one-carbon metabolism in MCF-7 cells as determined by (13)C NMR](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34897)
32. [MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34897)
33. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34897)
34. Ensembl Release 99