# Sequestosome 1

> mammalian protein found in Mus musculus

**Wikidata**: [Q21979991](https://www.wikidata.org/wiki/Q21979991)  
**Source**: https://4ort.xyz/entity/sequestosome-1-q21979991


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q64337)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64337)
5. [Cloning, expression profile, and genomic organization of the mouse STAP/A170 gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64337)
6. [TRAF6-mediated ubiquitination regulates nuclear translocation of NRIF, the p75 receptor interactor](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q64337)
7. [TRAF6-mediated ubiquitination regulates nuclear translocation of NRIF, the p75 receptor interactor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64337)
8. [Unc-51-like kinase 1/2-mediated endocytic processes regulate filopodia extension and branching of sensory axons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64337)
9. [The E3-ubiquitin ligase TRIM50 interacts with HDAC6 and p62, and promotes the sequestration and clearance of ubiquitinated proteins into the aggresome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64337)
10. [Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64337)
11. [p62/SQSTM1 by Binding to Vitamin D Receptor Inhibits Hepatic Stellate Cell Activity, Fibrosis, and Liver Cancer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64337)
12. [Bioinformatics and cellular signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64337)
13. [A role for NBR1 in autophagosomal degradation of ubiquitinated substrates](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64337)
14. [The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64337)
15. [p62 Targeting to the autophagosome formation site requires self-oligomerization but not LC3 binding](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64337)
16. [GOA](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q64337)
17. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64337)
18. [AMPA receptor trafficking and synaptic plasticity require SQSTM1/p62.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64337)
19. [The E3-ubiquitin ligase TRIM50 interacts with HDAC6 and p62, and promotes the sequestration and clearance of ubiquitinated proteins into the aggresome](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64337&geneProductId=UniProtKB:Q64337)
20. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64337&geneProductId=UniProtKB:Q64337)
21. [WIPI2 links LC3 conjugation with PI3P, autophagosome formation, and pathogen clearance by recruiting Atg12-5-16L1.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64337&geneProductId=UniProtKB:Q64337)
22. [Autophagy-regulating TP53INP2 mediates muscle wasting and is repressed in diabetes](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64337&geneProductId=UniProtKB:Q64337)
23. [Postfertilization autophagy of sperm organelles prevents paternal mitochondrial DNA transmission](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64337)
24. [In Vivo Evidence for Lysosome Depletion and Impaired Autophagic Clearance in Hereditary Spastic Paraplegia Type SPG11](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64337)
25. [WIPI2 links LC3 conjugation with PI3P, autophagosome formation, and pathogen clearance by recruiting Atg12-5-16L1.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64337)
26. [Autophagy-regulating TP53INP2 mediates muscle wasting and is repressed in diabetes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64337)
27. [Autophagy regulates phagocytosis by modulating the expression of scavenger receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64337)
28. ensembl Release 106