# Separase YGR098C

> fungal protein found in Saccharomyces cerevisiae S288c

**Wikidata**: [Q27548480](https://www.wikidata.org/wiki/Q27548480)  
**Source**: https://4ort.xyz/entity/separase-ygr098c


## References

1. UniProt
2. Q20641742
3. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03018)
4. [Cleavage of cohesin by the CD clan protease separin triggers anaphase in yeast](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03018&geneProductId=UniProtKB:Q03018)
5. [Molecular mechanism for the regulation of yeast separase by securin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03018)
6. [Separase cooperates with Zds1 and Zds2 to activate Cdc14 phosphatase in early anaphase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03018)
7. [High-quality binary protein interaction map of the yeast interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03018)
8. [Downregulation of PP2A(Cdc55) phosphatase by separase initiates mitotic exit in budding yeast.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03018)
9. [Disjunction of Homologous Chromosomes in Meiosis I Depends on Proteolytic Cleavage of the Meiotic Cohesin Rec8 by Separin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03018)
10. [Cleavage of cohesin by the CD clan protease separin triggers anaphase in yeast](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03018)
11. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03018)
12. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03018&geneProductId=UniProtKB:Q03018)
13. [A novel role of the budding yeast separin Esp1 in anaphase spindle elongation: evidence that proper spindle association of Esp1 is regulated by Pds1](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03018&geneProductId=UniProtKB:Q03018)
14. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03018&geneProductId=UniProtKB:Q03018)
15. [A novel role of the budding yeast separin Esp1 in anaphase spindle elongation: evidence that proper spindle association of Esp1 is regulated by Pds1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03018)
16. [Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03018)
17. [Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03018)
18. [The proteome of Saccharomyces cerevisiae mitochondria](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03018)
19. [The protease activity of yeast separase (esp1) is required for anaphase spindle elongation independently of its role in cleavage of cohesin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03018)
20. [An ESP1/PDS1 complex regulates loss of sister chromatid cohesion at the metaphase to anaphase transition in yeast](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03018)
21. [A non-proteolytic function of separase links the onset of anaphase to mitotic exit](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03018)
22. [Cleavage of Mcd1 by caspase-like protease Esp1 promotes apoptosis in budding yeast](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03018)
23. [Positive feedback promotes mitotic exit via the APC/C-Cdh1-separase-Cdc14 axis in budding yeast](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03018)
24. ensembl Release 106