# Senataxin

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21124479](https://www.wikidata.org/wiki/Q21124479)  
**Source**: https://4ort.xyz/entity/senataxin


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q7Z333)
3. Q20641742
4. [Human senataxin resolves RNA/DNA hybrids formed at transcriptional pause sites to promote Xrn2-dependent termination](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7Z333&geneProductId=UniProtKB:Q7Z333)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z333)
6. [Functional role for senataxin, defective in ataxia oculomotor apraxia type 2, in transcriptional regulation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z333)
7. [A SUMO-dependent interaction between Senataxin and the exosome, disrupted in the neurodegenerative disease AOA2, targets the exosome to sites of transcription-induced DNA damage](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z333)
8. [SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z333)
9. [A human MAP kinase interactome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z333)
10. [Protein interaction analysis of senataxin and the ALS4 L389S mutant yields insights into senataxin post-translational modification and uncovers mutant-specific binding with a brain cytoplasmic RNA-encoded peptide](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z333)
11. [Senataxin, defective in ataxia oculomotor apraxia type 2, is involved in the defense against oxidative DNA damage](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z333)
12. [Human senataxin resolves RNA/DNA hybrids formed at transcriptional pause sites to promote Xrn2-dependent termination](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z333)
13. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z333)
14. [Senataxin modulates neurite growth through fibroblast growth factor 8 signalling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z333)
15. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7Z333&geneProductId=UniProtKB:Q7Z333)
16. Ensembl Release 99