Semaphorin 5A
type: Thing
description: mammalian protein found in Homo sapiens
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P352
  value: Yopal
additional property: PropertyValue
  property ID: P361
  value: WD40/YVTN repeat-like-containing domain superfamily
additional property: PropertyValue
  property ID: P361
  value: Thrombospondin type-1 (TSP1) repeat superfamily
additional property: PropertyValue
  property ID: P361
  value: Sema domain superfamily
additional property: PropertyValue
  property ID: P527
  value: PSI domain
additional property: PropertyValue
  property ID: P527
  value: Thrombospondin type-1 (TSP1) repeat
additional property: PropertyValue
  property ID: P527
  value: Sema domain
additional property: PropertyValue
  property ID: P637
  value: NP_003957
additional property: PropertyValue
  property ID: P637
  value: XP_006714569
additional property: PropertyValue
  property ID: P637
  value: XP_006714570
additional property: PropertyValue
  property ID: P680
  value: chondroitin sulfate proteoglycan binding
additional property: PropertyValue
  property ID: P680
  value: heparan sulfate proteoglycan binding
additional property: PropertyValue
  property ID: P680
  value: syndecan binding
additional property: PropertyValue
  property ID: P681
  value: membrane
additional property: PropertyValue
  property ID: P681
  value: plasma membrane
additional property: PropertyValue
  property ID: P681
  value: extracellular exosome
additional property: PropertyValue
  property ID: P682
  value: negative regulation of endothelial cell apoptotic process
additional property: PropertyValue
  property ID: P682
  value: negative regulation of cell adhesion
additional property: PropertyValue
  property ID: P682
  value: cell differentiation
additional property: PropertyValue
  property ID: P702
  value: SEMA5A
additional property: PropertyValue
  property ID: P703
  value: Homo sapiens
additional property: PropertyValue
  property ID: P705
  value: ENSP00000371936
additional property: PropertyValue
  property ID: P705
  value: ENSP00000421961
additional property: PropertyValue
  property ID: P705
  value: ENSP00000499013
confidence:
  popularity graph score:
    score: 0.002
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 12
      unique citations norm: 0.005
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 12
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: Q13591
    source count: 1
    confidence: 0.2
    value label: Yopal
  P361:
    value: Q24784804
    source count: 1
    confidence: 0.2
    value label: WD40/YVTN repeat-like-containing domain superfamily
  P361:
    value: Q41797497
    source count: 1
    confidence: 0.2
    value label: Thrombospondin type-1 (TSP1) repeat superfamily
  P361:
    value: Q41797468
    source count: 1
    confidence: 0.2
    value label: Sema domain superfamily
  P361:
    value: Q24768287
    source count: 1
    confidence: 0.2
    value label: semaphorin
  P361:
    value: Q83138529
    source count: 1
    confidence: 0.2
    value label: Sema domain, protein family
  P527:
    value: Q24775891
    source count: 1
    confidence: 0.2
    value label: PSI domain
  P527:
    value: Q24772391
    source count: 1
    confidence: 0.2
    value label: Thrombospondin type-1 (TSP1) repeat
  P527:
    value: Q24768664
    source count: 1
    confidence: 0.2
    value label: Sema domain
  P637:
    value: NP_003957
    source count: 1
    confidence: 0.2
  P637:
    value: XP_006714569
    source count: 1
    confidence: 0.2
  P637:
    value: XP_006714570
    source count: 1
    confidence: 0.2
  P637:
    value: XP_011512457
    source count: 1
    confidence: 0.2
  P637:
    value: XP_011512458
    source count: 1
    confidence: 0.2
  P680:
    value: Q21122787
    source count: 1
    confidence: 0.2
    value label: chondroitin sulfate proteoglycan binding
  P680:
    value: Q14897884
    source count: 1
    confidence: 0.2
    value label: heparan sulfate proteoglycan binding
  P680:
    value: Q21541776
    source count: 1
    confidence: 0.2
    value label: syndecan binding
  P680:
    value: Q21122788
    source count: 1
    confidence: 0.2
    value label: semaphorin receptor binding
  P680:
    value: Q21122061
    source count: 1
    confidence: 0.2
    value label: neuropilin binding
  P681:
    value: Q14349455
    source count: 2
    confidence: 0.4
    value label: membrane
  P681:
    value: Q29548
    source count: 1
    confidence: 0.2
    value label: plasma membrane
  P681:
    value: Q903634
    source count: 2
    confidence: 0.4
    value label: extracellular exosome

value: Q14327652
source count: 1
confidence: 0.2
value label: integral component of membrane

value: Q1385443
source count: 1
confidence: 0.2
value label: extracellular space

value: Q14912175
source count: 1
confidence: 0.2
value label: negative regulation of endothelial cell apoptotic process

value: Q14911796
source count: 1
confidence: 0.2
value label: negative regulation of cell adhesion

value: Q210861
source count: 1
confidence: 0.2
value label: cell differentiation

value: Q14761970
source count: 1
confidence: 0.2
value label: positive regulation of protein kinase B signaling

value: Q14865064
source count: 1
confidence: 0.2
value label: positive regulation of endothelial cell proliferation

value: Q18033776
source count: 1
confidence: 0.2
value label: SEMA5A

value: Q15978631
source count: 1
confidence: 0.2
value label: Homo sapiens

value: ENSP00000371936
source count: 1
confidence: 0.2

value: ENSP00000421961
source count: 1
confidence: 0.2

value: ENSP00000499013
source count: 1
confidence: 0.2

source: GOA
stated in qid: Q28018111
retrieved: 2019-05-09

source: GOA
stated in qid: Q28018111
retrieved: 2017-09-26

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2019-04-08

source: Proteomic analysis of podocyte exosome-enriched fraction from normal human urine
stated in qid: Q24313258
retrieved: 2017-09-26

source: In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine
stated in qid: Q24337415
retrieved: 2017-09-26

source: In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine
stated in qid: Q24337415
retrieved: 2019-05-09

source: Molecular cloning and mapping of human semaphorin F from the Cri-du-chat candidate interval
stated in qid: Q24309540
retrieved: 2019-05-09

source: Isolation of cDNAs from the Cri-du-chat critical region by direct screening of a chromosome 5-specific cDNA library
stated in qid: Q24322966
retrieved: 2019-05-09

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2019-11-13

source: Q20641742
stated in qid: Q20641742
retrieved: 2020-05-30

source: Ensembl Release 99
stated in qid: Q83867711

wikidata id: Q21122789
domain: protein
level: standard
html url: https://4ort.xyz/entity/semaphorin-5a
markdown url: https://4ort.xyz/entity/semaphorin-5a.md
facts url summary: https://4ort.xyz/entity/semaphorin-5a/facts.json
facts url standard: https://4ort.xyz/entity/semaphorin-5a/facts.json
facts url full: https://4ort.xyz/entity/semaphorin-5a/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-10T07:23:39.484685Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T13:58:50.900290+00:00Z