# SEC61 translocon subunit alpha 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21110537](https://www.wikidata.org/wiki/Q21110537)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/Sec61_alpha_1)  
**Source**: https://4ort.xyz/entity/sec61-translocon-subunit-alpha-1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P61619)
3. Q20641742
4. [Palmitoylated calnexin is a key component of the ribosome-translocon complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61619)
5. [An AP-MS- and BioID-compatible MAC-tag enables comprehensive mapping of protein interactions and subcellular localizations](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61619)
6. [BiP-mediated closing of the Sec61 channel limits Ca2+ leakage from the ER](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61619)
7. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61619)
8. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61619)
9. [Plasma cell deficiency in human subjects with heterozygous mutations in Sec61 translocon alpha 1 subunit (SEC61A1).](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61619)
10. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61619&geneProductId=UniProtKB:P61619)
11. [Different effects of Sec61α, Sec62 and Sec63 depletion on transport of polypeptides into the endoplasmic reticulum of mammalian cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61619)
12. [Heterozygous Loss-of-Function SEC61A1 Mutations Cause Autosomal-Dominant Tubulo-Interstitial and Glomerulocystic Kidney Disease with Anemia](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61619&geneProductId=UniProtKB:P61619)
13. [Heterozygous Loss-of-Function SEC61A1 Mutations Cause Autosomal-Dominant Tubulo-Interstitial and Glomerulocystic Kidney Disease with Anemia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61619)
14. [Different effects of Sec61α, Sec62 and Sec63 depletion on transport of polypeptides into the endoplasmic reticulum of mammalian cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61619&geneProductId=UniProtKB:P61619)
15. [Chaperone-Mediated Sec61 Channel Gating during ER Import of Small Precursor Proteins Overcomes Sec61 Inhibitor-Reinforced Energy Barrier](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61619)
16. Ensembl Release 99
17. Transporter Classification database