# sclerostin

> mammalian protein found in Homo sapiens

**Wikidata**: [Q7434196](https://www.wikidata.org/wiki/Q7434196)  
**Source**: https://4ort.xyz/entity/sclerostin-q7434196


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q9BQB4)
3. Q20641742
4. [Control of the SOST bone enhancer by PTH using MEF2 transcription factors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BQB4)
5. [Bone overgrowth-associated mutations in the LRP4 gene impair sclerostin facilitator function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BQB4)
6. [Wnt antagonists bind through a short peptide to the first β-propeller domain of LRP5/6](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BQB4)
7. [SOST is a ligand for LRP5/LRP6 and a Wnt signaling inhibitor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BQB4)
8. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BQB4)
9. [Proteomics characterization of extracellular space components in the human aorta](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BQB4&geneProductId=UniProtKB:Q9BQB4)
10. [Proteomics characterization of extracellular space components in the human aorta](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BQB4)
11. [Osteocyte control of bone formation via sclerostin, a novel BMP antagonist](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BQB4)
12. [Sost down-regulation by mechanical strain in human osteoblastic cells involves PGE2 signaling via EP4](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BQB4)
13. [SOST is a ligand for LRP5/LRP6 and a Wnt signaling inhibitor](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BQB4&geneProductId=UniProtKB:Q9BQB4)
14. [Increased bone density in sclerosteosis is due to the deficiency of a novel secreted protein (SOST)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BQB4)
15. Ensembl Release 99
16. Identifiers.org
17. UMLS 2023