# RUNX family transcription factor 2

> mammalian protein found in Homo sapiens

**Wikidata**: [Q7277986](https://www.wikidata.org/wiki/Q7277986)  
**Source**: https://4ort.xyz/entity/runx-family-transcription-factor-2


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q13950)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13950)
5. [Mutations involving the transcription factor CBFA1 cause cleidocranial dysplasia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13950)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13950&geneProductId=UniProtKB:Q13950)
7. [Regulation of osteocalcin gene expression by a novel Ku antigen transcription factor complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13950)
8. [Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13950)
9. [MOZ and MORF histone acetyltransferases interact with the Runt-domain transcription factor Runx2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13950)
10. [Mitotic occupancy and lineage-specific transcriptional control of rRNA genes by Runx2.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13950)
11. [Runt-related transcription factor 2 attenuates the transcriptional activity as well as DNA damage-mediated induction of pro-apoptotic TAp73 to regulate chemosensitivity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13950)
12. [Transcriptional corepressor TLE1 functions with Runx2 in epigenetic repression of ribosomal RNA genes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13950)
13. [Smad6 interacts with Runx2 and mediates Smad ubiquitin regulatory factor 1-induced Runx2 degradation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13950)
14. [Wip1 promotes RUNX2-dependent apoptosis in p53-negative tumors and protects normal tissues during treatment with anticancer agents](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13950)
15. [Prolyl isomerase Pin1 enhances osteoblast differentiation through Runx2 regulation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13950)
16. [A census of human transcription factors: function, expression and evolution](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13950)
17. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13950)
18. [Functional analysis of novel RUNX2 mutations in cleidocranial dysplasia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13950)
19. [Analysis of novel RUNX2 mutations in Chinese patients with cleidocranial dysplasia.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13950)
20. [The RUNX1 Runt domain at 1.25A resolution: a structural switch and specifically bound chloride ions modulate DNA binding](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13950)
21. [Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13950)
22. [SLUG: a new target of lymphoid enhancer factor-1 in human osteoblasts](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13950)
23. [A novel RUNX2 mutation in exon 8, G462X, in a patient with Cleidocranial Dysplasia.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13950)
24. Ensembl Release 99
25. UMLS 2023