# Runt-related transcription factor 1

> mouse protein (annotated by UniProtKB/Swiss-Prot Q03347)

**Wikidata**: [Q15320472](https://www.wikidata.org/wiki/Q15320472)  
**Source**: https://4ort.xyz/entity/runt-related-transcription-factor-1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q03347)
3. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03347)
4. [Assembly and function of a TCR alpha enhancer complex is dependent on LEF-1-induced DNA bending and multiple protein-protein interactions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03347)
5. [Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03347)
6. [Twist-2 controls myeloid lineage development and function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03347)
7. [Transcription factor AP4 modulates reversible and epigenetic silencing of the Cd4 gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03347)
8. [T-bet represses T(H)17 differentiation by preventing Runx1-mediated activation of the gene encoding RORγt](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03347)
9. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03347)
10. [Mutagenesis of the Runt domain defines two energetic hot spots for heterodimerization with the core binding factor beta subunit](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03347)
11. [Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03347&geneProductId=UniProtKB:Q03347)
12. [Dynamic expression of Runx1 in skin affects hair structure](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03347)
13. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03347&geneProductId=UniProtKB:Q03347)
14. [Runx1 modulates adult hair follicle stem cell emergence and maintenance from distinct embryonic skin compartments](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03347&geneProductId=UniProtKB:Q03347)
15. [Transcription factor Runx1 inhibits proliferation and promotes developmental maturation in a selected population of inner olfactory nerve layer olfactory ensheathing cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03347&geneProductId=UniProtKB:Q03347)
16. [Cloning and characterization of subunits of the T-cell receptor and murine leukemia virus enhancer core-binding factor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03347)
17. [Repression of the transcription factor Th-POK by Runx complexes in cytotoxic T cell development.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03347)
18. [Transcription factor Runx1 inhibits proliferation and promotes developmental maturation in a selected population of inner olfactory nerve layer olfactory ensheathing cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03347)
19. [Runx1 modulates adult hair follicle stem cell emergence and maintenance from distinct embryonic skin compartments](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03347)
20. [Loss of Usp9x disrupts cortical architecture, hippocampal development and TGFβ-mediated axonogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03347)
21. [Overlapping expression of Runx1(Cbfa2) and Runx2(Cbfa1) transcription factors supports cooperative induction of skeletal development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03347)
22. [The haemangioblast generates haematopoietic cells through a haemogenic endothelium stage](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03347)
23. [Retinoic acid receptor gamma activates receptor tyrosine kinase Tie1 gene transcription through transcription factor GATA4 in F9 stem cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03347)
24. [Runx1 determines nociceptive sensory neuron phenotype and is required for thermal and neuropathic pain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03347)
25. [Runx1 function in hematopoiesis is required in cells that express Tek](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03347)
26. [A role for hematopoietic stem cells in promoting angiogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03347)
27. [AML1/Runx1 is important for the development of hindbrain cholinergic branchiovisceral motor neurons and selected cranial sensory neurons](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03347&geneProductId=UniProtKB:Q03347)
28. [Incoherent feed-forward regulatory loops control segregation of C-mechanoreceptors, nociceptors, and pruriceptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03347)
29. [HERF1, a novel hematopoiesis-specific RING finger protein, is required for terminal differentiation of erythroid cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03347)
30. [Functional and physical interactions between AML1 proteins and an ETS protein, MEF: implications for the pathogenesis of t(8;21)-positive leukemias](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03347&geneProductId=UniProtKB:Q03347)
31. [Functional and physical interactions between AML1 proteins and an ETS protein, MEF: implications for the pathogenesis of t(8;21)-positive leukemias](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03347)
32. [AML1/Runx1 is important for the development of hindbrain cholinergic branchiovisceral motor neurons and selected cranial sensory neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03347)