# Ring finger protein 8

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21118319](https://www.wikidata.org/wiki/Q21118319)  
**Source**: https://4ort.xyz/entity/ring-finger-protein-8-q21118319


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O76064)
3. Q20641742
4. [RNF168 Ubiquitinates K13-15 on H2A/H2AX to Drive DNA Damage Signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76064)
5. [RNF8 Ubiquitylates Histones at DNA Double-Strand Breaks and Promotes Assembly of Repair Proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=O76064&geneProductId=UniProtKB:O76064)
6. [RNF8 Transduces the DNA-Damage Signal via Histone Ubiquitylation and Checkpoint Protein Assembly](http://www.ebi.ac.uk/QuickGO/annotations?protein=O76064&geneProductId=UniProtKB:O76064)
7. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76064)
8. [RNF8‐ and RNF168‐dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76064)
9. [The E3 ligase RNF8 regulates KU80 removal and NHEJ repair](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76064)
10. [PCNA is ubiquitinated by RNF8](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76064)
11. [RNF8 Ubiquitylates Histones at DNA Double-Strand Breaks and Promotes Assembly of Repair Proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76064)
12. [RNF8 Transduces the DNA-Damage Signal via Histone Ubiquitylation and Checkpoint Protein Assembly](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76064)
13. [Differential regulation of RNF8-mediated Lys48- and Lys63-based poly-ubiquitylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76064)
14. [The scaffold protein WRAP53β orchestrates the ubiquitin response critical for DNA double-strand break repair](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76064)
15. [HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76064)
16. [DNA damage–inducible SUMOylation of HERC2 promotes RNF8 binding via a novel SUMO-binding Zinc finger](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76064)
17. [Phosphorylation of the Cajal body protein WRAP53β by ATM promotes its involvement in the DNA damage response](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76064)
18. [A comprehensive framework of E2–RING E3 interactions of the human ubiquitin–proteasome system](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76064)
19. [VRK1 phosphorylates and protects NBS1 from ubiquitination and proteasomal degradation in response to DNA damage](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76064)
20. [Towards a proteome-scale map of the human protein–protein interaction network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76064)
21. [A Proteome-Scale Map of the Human Interactome Network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76064)
22. [Next-generation sequencing to generate interactome datasets](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76064)
23. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76064)
24. [A Ubiquitin-Binding Protein, FAAP20, Links RNF8-Mediated Ubiquitination to the Fanconi Anemia DNA Repair Network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76064)
25. [ATM-Dependent Chromatin Changes Silence Transcription In cis to DNA Double-Strand Breaks](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76064)
26. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O76064&geneProductId=UniProtKB:O76064)
27. Ensembl Release 99