# Ring finger protein 139

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21118297](https://www.wikidata.org/wiki/Q21118297)  
**Source**: https://4ort.xyz/entity/ring-finger-protein-139-q21118297


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q8WU17)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8WU17&geneProductId=UniProtKB:Q8WU17)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WU17)
6. [The TRC8 E3 ligase ubiquitinates MHC class I molecules before dislocation from the ER](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8WU17&geneProductId=UniProtKB:Q8WU17)
7. [RING-dependent tumor suppression and G2/M arrest induced by the TRC8 hereditary kidney cancer gene](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8WU17&geneProductId=UniProtKB:Q8WU17)
8. [RING-dependent tumor suppression and G2/M arrest induced by the TRC8 hereditary kidney cancer gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WU17)
9. [Signal peptide peptidase functions in ERAD to cleave the unfolded protein response regulator XBP 1u](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WU17)
10. [The sterol-sensing endoplasmic reticulum (ER) membrane protein TRC8 hampers ER to Golgi transport of sterol regulatory element-binding protein-2 (SREBP-2)/SREBP cleavage-activated protein and reduces SREBP-2 cleavage](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WU17)
11. [The TRC8 E3 ligase ubiquitinates MHC class I molecules before dislocation from the ER](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WU17)
12. [The TRC8 hereditary kidney cancer gene suppresses growth and functions with VHL in a common pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WU17)
13. [RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8WU17&geneProductId=UniProtKB:Q8WU17)
14. [The hereditary renal cell carcinoma 3;8 translocation fuses FHIT to a patched- related gene, TRC8](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WU17)
15. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WU17)
16. [RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WU17)
17. [The TRC8 hereditary kidney cancer gene suppresses growth and functions with VHL in a common pathway](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8WU17&geneProductId=UniProtKB:Q8WU17)
18. [The TRC8 ubiquitin ligase is sterol regulated and interacts with lipid and protein biosynthetic pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WU17)
19. [Signal peptide peptidase functions in ERAD to cleave the unfolded protein response regulator XBP 1u](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8WU17&geneProductId=UniProtKB:Q8WU17)
20. Ensembl Release 99