Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
type: Thing
description: mammalian protein found in Rattus norvegicus
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P361
  value: Zinc finger, FYVE/PHD-type
additional property: PropertyValue
  property ID: P361
  value: Zinc finger, RING/FYVE/PHD-type
additional property: PropertyValue
  property ID: P361
  value: SAP domain superfamily
additional property: PropertyValue
  property ID: P527
  value: Zinc finger, RING-type
additional property: PropertyValue
  property ID: P637
  value: NP_001004068
additional property: PropertyValue
  property ID: P637
  value: XP_006247031
additional property: PropertyValue
  property ID: P637
  value: XP_006247032
additional property: PropertyValue
  property ID: P680
  value: protease binding
additional property: PropertyValue
  property ID: P680
  value: p53 binding
additional property: PropertyValue
  property ID: P680
  value: transferase activity
additional property: PropertyValue
  property ID: P681
  value: tumor necrosis factor receptor superfamily complex
additional property: PropertyValue
  property ID: P681
  value: cytoplasm
additional property: PropertyValue
  property ID: P681
  value: endosome
additional property: PropertyValue
  property ID: P682
  value: ubiquitin-dependent protein catabolic process
additional property: PropertyValue
  property ID: P682
  value: apoptotic process
additional property: PropertyValue
  property ID: P682
  value: regulation of fibroblast migration
additional property: PropertyValue
  property ID: P702
  value: Rffl
additional property: PropertyValue
  property ID: P703
  value: brown rat
confidence:
  popularity graph score:
    score: 0.001
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 5
      unique citations norm: 0.002
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 5
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: Q8CIN9
    source count: 1
    confidence: 0.2
  P361:
    value: Q24719950
    source count: 1
    confidence: 0.2
    value label: Zinc finger, FYVE/PHD-type
  P361:
    value: Q24786519
    source count: 1
    confidence: 0.2
    value label: Zinc finger, RING/FYVE/PHD-type
  P361:
    value: Q41797475
    source count: 1
    confidence: 0.2
    value label: SAP domain superfamily
  P361:
    value: Q423042
    source count: 1
    confidence: 0.2
    value label: membrane protein
  P361:
    value: Q83166628
    source count: 1
    confidence: 0.2
    value label: Zinc finger, RING-type, protein family
  P527:
    value: Q24788168
    source count: 1
    confidence: 0.2
    value label: Zinc finger, RING-type
  P637:
    value: NP_001004068
    source count: 1
    confidence: 0.2
  P637:
    value: XP_006247031
    source count: 1
    confidence: 0.2
  P637:
    value: XP_006247032
    source count: 1
    confidence: 0.2
  P637:
    value: XP_006247035
    source count: 1
    confidence: 0.2
  P637:
    value: XP_006247036
    source count: 1
    confidence: 0.2
  P680:
    value: Q14758894
    source count: 1
    confidence: 0.2
    value label: protease binding
  P680:
    value: Q14817974
    source count: 1
    confidence: 0.2
    value label: p53 binding
  P680:
    value: Q14840131
    source count: 1
    confidence: 0.2
    value label: transferase activity
  P680:
    value: Q14817984
    source count: 1
    confidence: 0.2
    value label: protein kinase binding
  P680:
    value: Q14633869
    source count: 1
    confidence: 0.2
    value label: ubiquitin protein ligase binding
  P681:
    value: Q22328479
    source count: 2
    confidence: 0.4
    value label: tumor necrosis factor receptor superfamily complex
  P681:
    value: Q79899
    source count: 2
    confidence: 0.4
    value label: cytoplasm
  P681:
    value: Q824237
    source count: 1
    confidence: 0.2
    value label: endosome
  P681:
    value: Q220599
    source count: 1
    confidence: 0.2
    value label: cytosol
  P681:
    value: Q29548
    source count: 2
    confidence: 0.4
    value label: plasma membrane
  P682:
    value: Q14864233
    source count: 2
    confidence: 0.4
    value label: ubiquitin-dependent protein catabolic process
  P682:
    value: Q14599311
    source count: 1
    confidence: 0.2
    value label: apoptotic process
  P682:
    value: Q21100594
    source count: 1
    confidence: 0.2
    value label: regulation of fibroblast migration

value: Q14864024
source count: 2
confidence: 0.4
value label: negative regulation of tumor necrosis factor-mediated signaling pathway

value: Q3547638
source count: 1
confidence: 0.2
value label: protein ubiquitination

value: Q24394740
source count: 1
confidence: 0.2
value label: Rffl

value: Q184224
source count: 1
confidence: 0.2
value label: brown rat

source: GOA
stated in qid: Q28018111
retrieved: 2017-09-16

source: GOA
stated in qid: Q28018111
retrieved: 2019-02-14

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2022-05-25

source: Q20641742
stated in qid: Q20641742
retrieved: 2022-03-20

wikidata id: Q28555988
domain: protein
level: standard
html url: https://4ort.xyz/entity/ring-finger-and-fyve-like-domain-containing-e3-ubiquitin-protein-ligase
markdown url: https://4ort.xyz/entity/ring-finger-and-fyve-like-domain-containing-e3-ubiquitin-protein-ligase.md
facts url summary: https://4ort.xyz/entity/ring-finger-and-fyve-like-domain-containing-e3-ubiquitin-protein-ligase/facts.json
facts url standard: https://4ort.xyz/entity/ring-finger-and-fyve-like-domain-containing-e3-ubiquitin-protein-ligase/facts.json
facts url full: https://4ort.xyz/entity/ring-finger-and-fyve-like-domain-containing-e3-ubiquitin-protein-ligase/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-04T16:14:41.639087Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T14:26:41.845951+00:00Z