# Rhomboid Dmel_CG1004

> protein found in Drosophila melanogaster

**Wikidata**: [Q29819552](https://www.wikidata.org/wiki/Q29819552)  
**Source**: https://4ort.xyz/entity/rhomboid-dmel-cg1004


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P20350)
3. Q20641742
4. [Drosophila rhomboid-1 defines a family of putative intramembrane serine proteases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20350)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20350)
6. [Mechanism of activation of the Drosophila EGF Receptor by the TGFalpha ligand Gurken during oogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20350)
7. [Rhomboid cleaves Star to regulate the levels of secreted Spitz](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20350)
8. [Conservation of intramembrane proteolytic activity and substrate specificity in prokaryotic and eukaryotic rhomboids](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20350)
9. [Regulated Intracellular Ligand Transport and Proteolysis Control EGF Signal Activation in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20350)
10. [Keren, a new ligand of the Drosophila epidermal growth factor receptor, undergoes two modes of cleavage](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20350)
11. [Generation of distinct signaling modes via diversification of the Egfr ligand-processing cassette.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20350)
12. [A family of Rhomboid intramembrane proteases activates all Drosophila membrane-tethered EGF ligands](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20350)
13. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20350)
14. [Polarized secretion of Drosophila EGFR ligand from photoreceptor neurons is controlled by ER localization of the ligand-processing machinery](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20350)
15. [A genome-wide resource for the analysis of protein localisation in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20350)
16. [Molecular requirements for actin-based lamella formation in Drosophila S2 cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20350)
17. [Genetic control of branching morphogenesis during Drosophila tracheal development.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P20350&geneProductId=UniProtKB:P20350)
18. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P20350&geneProductId=UniProtKB:P20350)
19. [Localized activation of RTK/MAPK pathways during Drosophila development](http://www.ebi.ac.uk/QuickGO/annotations?protein=P20350&geneProductId=UniProtKB:P20350)
20. [Novel interplay between JNK and Egfr signaling in Drosophila dorsal closure](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20350)
21. [Projections of Drosophila multidendritic neurons in the central nervous system: links with peripheral dendrite morphology](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20350)
22. [A function for Egf receptor signaling in expanding the developing brain in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20350)
23. [Mutations affecting the pattern of the PNS in Drosophila reveal novel aspects of neuronal development](http://www.ebi.ac.uk/QuickGO/annotations?protein=P20350&geneProductId=UniProtKB:P20350)
24. [Organ formation in Drosophila: specification and morphogenesis of the salivary gland.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P20350&geneProductId=UniProtKB:P20350)
25. [Drosophila tracheal morphogenesis: intricate cellular solutions to basic plumbing problems](http://www.ebi.ac.uk/QuickGO/annotations?protein=P20350&geneProductId=UniProtKB:P20350)
26. [Tube morphogenesis: closure, but many openings remain](http://www.ebi.ac.uk/QuickGO/annotations?protein=P20350&geneProductId=UniProtKB:P20350)
27. [Branching morphogenesis of the Drosophila tracheal system.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P20350&geneProductId=UniProtKB:P20350)
28. [Constructing an organ: the Drosophila salivary gland as a model for tube formation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P20350&geneProductId=UniProtKB:P20350)
29. [A targeted gain-of-function screen identifies genes affecting salivary gland morphogenesis/tubulogenesis in Drosophila.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20350)
30. [abdominal A specifies one cell type in Drosophila by regulating one principal target gene.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20350)
31. [Blistered: a gene required for vein/intervein formation in wings of Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?protein=P20350&geneProductId=UniProtKB:P20350)
32. [Pattern formation in the Drosophila wing: The development of the veins](http://www.ebi.ac.uk/QuickGO/annotations?protein=P20350&geneProductId=UniProtKB:P20350)
33. [MAP kinase subcellular localization controls both pattern and proliferation in the developing Drosophila wing](http://www.ebi.ac.uk/QuickGO/annotations?protein=P20350&geneProductId=UniProtKB:P20350)
34. [Regulation of Drosophila wing vein patterning: net encodes a bHLH protein repressing rhomboid and is repressed by rhomboid-dependent Egfr signalling](http://www.ebi.ac.uk/QuickGO/annotations?protein=P20350&geneProductId=UniProtKB:P20350)
35. [Epidermal growth factor receptor and transforming growth factor-beta signaling contributes to variation for wing shape in Drosophila melanogaster](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20350)
36. [Developmental biology: signalling legacies](http://www.ebi.ac.uk/QuickGO/annotations?protein=P20350&geneProductId=UniProtKB:P20350)
37. [High mobility group proteins HMGD and HMGZ interact genetically with the Brahma chromatin remodeling complex in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20350)
38. [Long-range Dpp signaling is regulated to restrict BMP signaling to a crossvein competent zone.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20350)
39. [MAP kinase subcellular localization controls both pattern and proliferation in the developing Drosophila wing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20350)
40. [Regulation of Drosophila wing vein patterning: net encodes a bHLH protein repressing rhomboid and is repressed by rhomboid-dependent Egfr signalling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20350)
41. [Integration of epithelial patterning and morphogenesis in Drosophila ovarian follicle cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P20350&geneProductId=UniProtKB:P20350)
42. [Egfr is essential for maintaining epithelial integrity during tracheal remodelling in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20350)
43. [Allocation and specification of the genital disc precursor cells in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20350)
44. [Rhomboid family pseudoproteases use the ER quality control machinery to regulate intercellular signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20350)
45. [The polarisation of the anterior-posterior and dorsal-ventral axes during Drosophila oogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P20350&geneProductId=UniProtKB:P20350)
46. [Cell fate choices in Drosophila tracheal morphogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P20350&geneProductId=UniProtKB:P20350)
47. [Happyhour, a Ste20 family kinase, implicates EGFR signaling in ethanol-induced behaviors.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20350)
48. [Ethanol sensitivity and tolerance in long-term memory mutants of Drosophila melanogaster](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20350)
49. [Drosophila adult muscle precursors form a network of interconnected cells and are specified by the rhomboid-triggered EGF pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20350)
50. [Seven-up, the Drosophila homolog of the COUP-TF orphan receptors, controls cell proliferation in the insect kidney](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20350)