# Rho/rac guanine nucleotide exchange factor (GEF) 2

> mammalian protein found in Mus musculus

**Wikidata**: [Q21494878](https://www.wikidata.org/wiki/Q21494878)  
**Source**: https://4ort.xyz/entity/rho-rac-guanine-nucleotide-exchange-factor-gef-2


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q60875)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875)
5. [The Rho-specific GEF Lfc interacts with neurabin and spinophilin to regulate dendritic spine morphology](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875)
6. [Calpain-6, a microtubule-stabilizing protein, regulates Rac1 activity and cell motility through interaction with GEF-H1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875)
7. [GEFH1 binds ASAP1 and regulates podosome formation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875)
8. [The RhoGEF GEF-H1 is required for oncogenic RAS signaling via KSR-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875)
9. [Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875)
10. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60875&geneProductId=UniProtKB:Q60875)
11. [Lfc and Tctex-1 regulate the genesis of neurons from cortical precursor cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875)
12. [Homozygous ARHGEF2 mutation causes intellectual disability and midbrain-hindbrain malformation.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875)
13. ensembl Release 106