# Rho guanine nucleotide exchange factor (GEF7)

> mammalian protein found in Mus musculus

**Wikidata**: [Q21496092](https://www.wikidata.org/wiki/Q21496092)  
**Source**: https://4ort.xyz/entity/rho-guanine-nucleotide-exchange-factor-gef7-


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q9ES28)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ES28&geneProductId=UniProtKB:Q9ES28)
5. [Cool-1/βPIX functions as a guanine nucleotide exchange factor in the cycling of Cdc42 to regulate insulin secretion](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ES28&geneProductId=UniProtKB:Q9ES28)
6. [A tyrosine-phosphorylated protein that binds to an important regulatory region on the cool family of p21-activated kinase-binding proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ES28&geneProductId=UniProtKB:Q9ES28)
7. [Bioinformatics and cellular signaling](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ES28&geneProductId=UniProtKB:Q9ES28)
8. [An Integrin-Linked Machinery of Cytoskeletal Regulation that Enables Experimental Tumor Initiation and Metastatic Colonization](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ES28&geneProductId=UniProtKB:Q9ES28)
9. [Proteomics analysis of immuno-precipitated synaptic protein complexes](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ES28&geneProductId=UniProtKB:Q9ES28)
10. [N-α-acetyltransferase 10 protein suppresses cancer cell metastasis by binding PIX proteins and inhibiting Cdc42/Rac1 activity](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ES28&geneProductId=UniProtKB:Q9ES28)
11. [Transgenic mouse proteomics identifies new 14-3-3-associated proteins involved in cytoskeletal rearrangements and cell signaling](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ES28&geneProductId=UniProtKB:Q9ES28)
12. [Affixin activates Rac1 via betaPIX in C2C12 myoblast](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ES28&geneProductId=UniProtKB:Q9ES28)
13. [The Shank family of postsynaptic density proteins interacts with and promotes synaptic accumulation of the beta PIX guanine nucleotide exchange factor for Rac1 and Cdc42](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ES28&geneProductId=UniProtKB:Q9ES28)
14. [ARHGEF7 (Beta-PIX) acts as guanine nucleotide exchange factor for leucine-rich repeat kinase 2](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ES28&geneProductId=UniProtKB:Q9ES28)
15. [Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ES28&geneProductId=UniProtKB:Q9ES28)
16. [Haploinsufficiency of SAMD9L, an Endosome Fusion Facilitator, Causes Myeloid Malignancies in Mice Mimicking Human Diseases with Monosomy 7](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ES28&geneProductId=UniProtKB:Q9ES28)
17. ensembl Release 106