Rho-associated protein kinase let-502 CELE_C10H11.9
protein kinase C-like, phorbol ester/diacylglycerol-binding domain
protein serine/threonine kinase activity
Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, protein family
AGC-kinase, C-terminal domain, protein family
serine/threonine-protein kinase, active site
Caenorhabditis elegans LET-502 is related to Rho-binding kinases and human myotonic dystrophy kinase and interacts genetically with a homolog of the regulatory subunit of smooth muscle myosin phosphatase to affect cell shape
The Caenorhabditis elegans mel-11 myosin phosphatase regulatory subunit affects tissue contraction in the somatic gonad and the embryonic epidermis and genetically interacts with the Rac signaling pathway
TheCaenorhabditis elegansnonmuscle myosin genesnmy-1andnmy-2function as redundant components of thelet-502/Rho-binding kinase andmel-11/myosin phosphatase pathway during embryonic morphogenesis
Cell architecture: surrounding muscle cells shape gland cell morphology in the Caenorhabditis elegans pharynx
Myosin II regulation during C. elegans embryonic elongation: LET-502/ROCK, MRCK-1 and PAK-1, three kinases with different roles