# Retinoid isomerohydrolase RPE65

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21123400](https://www.wikidata.org/wiki/Q21123400)  
**Source**: https://4ort.xyz/entity/retinoid-isomerohydrolase-rpe65


## References

1. UniProt
2. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL2107821)
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q16518)
4. Q20641742
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16518)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16518&geneProductId=UniProtKB:Q16518)
7. [RPE65 has an additional function as the lutein to meso-zeaxanthin isomerase in the vertebrate eye.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16518)
8. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16518)
9. [Identification of Key Residues Determining Isomerohydrolase Activity of Human RPE65](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16518)
10. [Insights into the pathogenesis of dominant retinitis pigmentosa associated with a D477G mutation in RPE65.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16518)
11. [A homozygosity-based search for mutations in patients with autosomal recessive retinitis pigmentosa, using microsatellite markers](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16518)
12. [Mutations in RPE65 cause autosomal recessive childhood–onset severe retinal dystrophy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16518)
13. [RPE65 has an additional function as the lutein to meso-zeaxanthin isomerase in the vertebrate eye.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16518&geneProductId=UniProtKB:Q16518)
14. Ensembl Release 99