# retinoic acid receptor alpha

> mammalian protein found in Homo sapiens

**Wikidata**: [Q254943](https://www.wikidata.org/wiki/Q254943)  
**Source**: https://4ort.xyz/entity/retinoic-acid-receptor-alpha-q254943


## References

1. UniProt
2. IUPHAR/BPS Guide to PHARMACOLOGY
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P10276)
4. Q20641742
5. Freebase Data Dumps. 2013
6. [A human retinoic acid receptor which belongs to the family of nuclear receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10276)
7. [Cooperative interaction between retinoic acid receptor-alpha and estrogen receptor in breast cancer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10276)
8. [Human ADA3 regulates RARalpha transcriptional activity through direct contact between LxxLL motifs and the receptor coactivator pocket](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10276)
9. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10276)
10. [Retinoic acid-dependent activation of the polycystic kidney disease-1 (PKD1) promoter](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10276)
11. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10276&geneProductId=UniProtKB:P10276)
12. [Induction of transglutaminase 2 by a liver X receptor/retinoic acid receptor alpha pathway increases the clearance of apoptotic cells by human macrophages](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10276)
13. [Loss of CAK phosphorylation of RAR{alpha} mediates transcriptional control of retinoid-induced cancer cell differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10276)
14. [MED25 is distinct from TRAP220/MED1 in cooperating with CBP for retinoid receptor activation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10276&geneProductId=UniProtKB:P10276)
15. [Identification of protein arginine methyltransferase 2 as a coactivator for estrogen receptor alpha](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10276)
16. [Two distinct nuclear receptor interaction domains in NSD1, a novel SET protein that exhibits characteristics of both corepressors and coactivators](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10276)
17. [Small ubiquitin-like modifier-2 modification of retinoic acid receptor-alpha regulates its subcellular localization and transcriptional activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10276)
18. [P38MAPK-dependent phosphorylation and degradation of SRC-3/AIB1 and RARalpha-mediated transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10276)
19. [The TRAP220 component of a thyroid hormone receptor- associated protein (TRAP) coactivator complex interacts directly with nuclear receptors in a ligand-dependent fashion](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10276)
20. [Role of the polycomb repressive complex 2 in acute promyelocytic leukemia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10276)
21. [LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10276)
22. [MED25 is distinct from TRAP220/MED1 in cooperating with CBP for retinoid receptor activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10276)
23. [The histone demethylase PHF8 governs retinoic acid response in acute promyelocytic leukemia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10276)
24. [Small ubiquitin-related modifier-1 modification regulates all-trans-retinoic acid-induced differentiation via stabilization of retinoic acid receptor α](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10276)
25. [Familial focal segmental glomerulosclerosis (FSGS)-linked α-actinin 4 (ACTN4) protein mutants lose ability to activate transcription by nuclear hormone receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10276)
26. [ZNF423 is critically required for retinoic acid-induced differentiation and is a marker of neuroblastoma outcome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10276)
27. [A unique secondary-structure switch controls constitutive gene repression by retinoic acid receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10276)
28. [Towards a proteome-scale map of the human protein–protein interaction network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10276)
29. [Identification of retinoic acid as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10276)
30. [A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10276)
31. [Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10276)
32. [A retinoic acid receptor RARα pool present in membrane lipid rafts forms complexes with G protein αQ to activate p38MAPK](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10276)
33. [Enhancer activation requires trans-recruitment of a mega transcription factor complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10276)
34. [Using an in Situ Proximity Ligation Assay to Systematically Profile Endogenous Protein–Protein Interactions in a Pathway Network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10276)
35. [Additional sex comb-like 1 (ASXL1), in cooperation with SRC-1, acts as a ligand-dependent coactivator for retinoic acid receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10276)
36. [Common architecture of nuclear receptor heterodimers on DNA direct repeat elements with different spacings](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10276)
37. [Next-generation sequencing to generate interactome datasets](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10276)
38. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10276)
39. [Toward an understanding of the protein interaction network of the human liver](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10276)
40. [Reciprocal roles of SIRT1 and SKIP in the regulation of RAR activity: implication in the retinoic acid-induced neuronal differentiation of P19 cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10276)
41. [Phosphorylation by PKA potentiates retinoic acid receptor alpha activity by means of increasing interaction with and phosphorylation by cyclin H/cdk7.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10276)
42. [The core component of the mammalian SWI/SNF complex SMARCD3/BAF60c is a coactivator for the nuclear retinoic acid receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10276)
43. [Activity of Retinoic Acid Receptor-alpha Is Directly Regulated at Its Protein Kinase A Sites in Response to Follicle-Stimulating Hormone Signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10276)
44. [Akt phosphorylates and suppresses the transactivation of retinoic acid receptor alpha](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10276)
45. [A census of human transcription factors: function, expression and evolution](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10276&geneProductId=UniProtKB:P10276)
46. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10276)
47. [A census of human transcription factors: function, expression and evolution](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10276)
48. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10276&geneProductId=UniProtKB:P10276)
49. [A human retinoic acid receptor which belongs to the family of nuclear receptors](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10276&geneProductId=UniProtKB:P10276)
50. [Loss of CAK phosphorylation of RAR{alpha} mediates transcriptional control of retinoid-induced cancer cell differentiation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10276&geneProductId=UniProtKB:P10276)