# Replication protein A2

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21115044](https://www.wikidata.org/wiki/Q21115044)  
**Source**: https://4ort.xyz/entity/replication-protein-a2-q21115044


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P15927)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15927)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15927&geneProductId=UniProtKB:P15927)
6. [Evidence for direct contact between the RPA3 subunit of the human replication protein A and single-stranded DNA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15927&geneProductId=UniProtKB:P15927)
7. [The primary structure of the 32-kDa subunit of human replication protein A](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15927&geneProductId=UniProtKB:P15927)
8. [Activation of the ATR kinase by the RPA-binding protein ETAA1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15927)
9. [RPA involvement in the damage-recognition and incision steps of nucleotide excision repair](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15927)
10. [ETAA1 acts at stalled replication forks to maintain genome integrity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15927)
11. [The 32-kilodalton subunit of replication protein A interacts with menin, the product of the MEN1 tumor suppressor gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15927)
12. [Removal of RTF2 from Stalled Replisomes Promotes Maintenance of Genome Integrity.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15927)
13. [Physical interaction between human RAD52 and RPA is required for homologous recombination in mammalian cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15927)
14. [A PP4 phosphatase complex dephosphorylates RPA2 to facilitate DNA repair via homologous recombination](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15927)
15. [RFWD3-Mediated Ubiquitination Promotes Timely Removal of Both RPA and RAD51 from DNA Damage Sites to Facilitate Homologous Recombination](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15927)
16. [RPA-Mediated Recruitment of the E3 Ligase RFWD3 Is Vital for Interstrand Crosslink Repair and Human Health](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15927)
17. [RPA mediates recombination repair during replication stress and is displaced from DNA by checkpoint signalling in human cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15927)
18. [Interaction and colocalization of Rad9/Rad1/Hus1 checkpoint complex with replication protein A in human cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15927)
19. [A human protein-protein interaction network: a resource for annotating the proteome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15927)
20. [Cell cycle-dependent formation of Cdc45-Claspin complexes in human cells is compromized by UV-mediated DNA damage](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15927)
21. [The crystal structure of the complex of replication protein A subunits RPA32 and RPA14 reveals a mechanism for single-stranded DNA binding](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15927)
22. [Structure of RPA32 bound to the N-terminus of SMARCAL1 redefines the binding interface between RPA32 and its interacting proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15927)
23. [Insights into eukaryotic DNA priming from the structure and functional interactions of the 4Fe-4S cluster domain of human DNA primase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15927)
24. [Mechanism of the ATP-dependent DNA end-resection machinery from Saccharomyces cerevisiae.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15927)
25. [A human interactome in three quantitative dimensions organized by stoichiometries and abundances](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15927)
26. [The role of human single-stranded DNA binding protein and its individual subunits in simian virus 40 DNA replication](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15927)
27. [4E‐BP3 regulates eIF4E‐mediated nuclear mRNA export and interacts with replication protein A2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15927)
28. [SIRT1 Regulates UV-Induced DNA Repair through Deacetylating XPA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15927)
29. [Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15927)
30. [RBT1, a novel transcriptional co-activator, binds the second subunit of replication protein A](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15927)
31. [Structure of the RPA trimerization core and its role in the multistep DNA-binding mechanism of RPA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15927)
32. [Physical and functional mapping of the replication protein a interaction domain of the werner and bloom syndrome helicases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15927)
33. [Streamline proteomic approach for characterizing protein-protein interaction network in a RAD52 protein complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15927)
34. [hPrimpol1/CCDC111 is a human DNA primase‐polymerase required for the maintenance of genome integrity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15927)
35. [Interaction between BRCA2 and replication protein A is compromised by a cancer-predisposing mutation in BRCA2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15927)
36. [The annealing helicase HARP is recruited to DNA repair sites via an interaction with RPA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15927)
37. [The SIOD disorder protein SMARCAL1 is an RPA-interacting protein involved in replication fork restart](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15927)
38. [E3 Ligase RFWD3 Participates in Replication Checkpoint Control](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15927)
39. [Binding polarity of RPA to telomeric sequences and influence of G-quadruplex stability](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15927)
40. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15927)
41. [Evidence for direct contact between the RPA3 subunit of the human replication protein A and single-stranded DNA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15927)
42. [The primary structure of the 32-kDa subunit of human replication protein A](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15927)
43. [E3 Ligase RFWD3 Participates in Replication Checkpoint Control](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15927&geneProductId=UniProtKB:P15927)
44. [ATR kinase activity regulates the intranuclear translocation of ATR and RPA following ionizing radiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15927)
45. [Replication protein A prevents accumulation of single-stranded telomeric DNA in cells that use alternative lengthening of telomeres](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15927)
46. [Replication protein A prevents accumulation of single-stranded telomeric DNA in cells that use alternative lengthening of telomeres](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15927&geneProductId=UniProtKB:P15927)
47. [Sumoylation of the novel protein hRIP{beta} is involved in replication protein A deposition in PML nuclear bodies](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15927&geneProductId=UniProtKB:P15927)
48. [ETAA1 acts at stalled replication forks to maintain genome integrity](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15927&geneProductId=UniProtKB:P15927)
49. [Structure of the RPA trimerization core and its role in the multistep DNA-binding mechanism of RPA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15927&geneProductId=UniProtKB:P15927)
50. [Activation of the ATR kinase by the RPA-binding protein ETAA1](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15927&geneProductId=UniProtKB:P15927)