# Replication protein A1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21109589](https://www.wikidata.org/wiki/Q21109589)  
**Source**: https://4ort.xyz/entity/replication-protein-a1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P27694)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27694&geneProductId=UniProtKB:P27694)
6. [Structure of the single-stranded-DNA-binding domain of replication protein A bound to DNA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27694&geneProductId=UniProtKB:P27694)
7. [Evidence for direct contact between the RPA3 subunit of the human replication protein A and single-stranded DNA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27694&geneProductId=UniProtKB:P27694)
8. [ETAA1 acts at stalled replication forks to maintain genome integrity](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27694&geneProductId=UniProtKB:P27694)
9. [RPA involvement in the damage-recognition and incision steps of nucleotide excision repair](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27694&geneProductId=UniProtKB:P27694)
10. [Activation of the ATR kinase by the RPA-binding protein ETAA1](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27694&geneProductId=UniProtKB:P27694)
11. [Activation of the ATR kinase by the RPA-binding protein ETAA1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694)
12. [Replication protein A physically interacts with the Bloom's syndrome protein and stimulates its helicase activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694)
13. [RPA involvement in the damage-recognition and incision steps of nucleotide excision repair](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694)
14. [SLFN11 Blocks Stressed Replication Forks Independently of ATR.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694)
15. [Interaction of DNA polymerase alpha-primase with cellular replication protein A and SV40 T antigen](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694)
16. [ETAA1 acts at stalled replication forks to maintain genome integrity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694)
17. [Interaction and colocalization of Rad9/Rad1/Hus1 checkpoint complex with replication protein A in human cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694)
18. [Functional and physical interaction between WRN helicase and human replication protein A](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694)
19. [Timed interactions between viral and cellular replication factors during the initiation of SV40 in vitro DNA replication](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694)
20. [Mechanism of the ATP-dependent DNA end-resection machinery from Saccharomyces cerevisiae.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694)
21. [BLAP75, an essential component of Bloom's syndrome protein complexes that maintain genome integrity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694)
22. [A human interactome in three quantitative dimensions organized by stoichiometries and abundances](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694)
23. [The role of human single-stranded DNA binding protein and its individual subunits in simian virus 40 DNA replication](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694)
24. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694)
25. [Different activities of the largest subunit of replication protein A cooperate during SV40 DNA replication](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694)
26. [Structure of the RPA trimerization core and its role in the multistep DNA-binding mechanism of RPA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694)
27. [Physical and functional mapping of the replication protein a interaction domain of the werner and bloom syndrome helicases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694)
28. [Streamline proteomic approach for characterizing protein-protein interaction network in a RAD52 protein complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694)
29. [p53 modulates RPA-dependent and RPA-independent WRN helicase activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694)
30. [hPrimpol1/CCDC111 is a human DNA primase‐polymerase required for the maintenance of genome integrity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694)
31. [Interaction between BRCA2 and replication protein A is compromised by a cancer-predisposing mutation in BRCA2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694)
32. [RPA prevents G-rich structure formation at lagging-strand telomeres to allow maintenance of chromosome ends](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694)
33. [Binding polarity of RPA to telomeric sequences and influence of G-quadruplex stability](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694)
34. [Human replication protein A unfolds telomeric G-quadruplexes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694)
35. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694)
36. [Structure of the single-stranded-DNA-binding domain of replication protein A bound to DNA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694)
37. [Evidence for direct contact between the RPA3 subunit of the human replication protein A and single-stranded DNA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694)
38. [Replication protein A prevents accumulation of single-stranded telomeric DNA in cells that use alternative lengthening of telomeres](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694)
39. [Sumoylation of the novel protein hRIP{beta} is involved in replication protein A deposition in PML nuclear bodies](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694)
40. [Sumoylation of the novel protein hRIP{beta} is involved in replication protein A deposition in PML nuclear bodies](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27694&geneProductId=UniProtKB:P27694)
41. [Structure of the RPA trimerization core and its role in the multistep DNA-binding mechanism of RPA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27694&geneProductId=UniProtKB:P27694)
42. [WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694)
43. [Functional domains of the 70-kilodalton subunit of human replication protein A](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27694&geneProductId=UniProtKB:P27694)
44. [Functional domains of the 70-kilodalton subunit of human replication protein A](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694)
45. [The evolutionarily conserved zinc finger motif in the largest subunit of human replication protein A is required for DNA replication and mismatch repair but not for nucleotide excision repair](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694)
46. [The evolutionarily conserved zinc finger motif in the largest subunit of human replication protein A is required for DNA replication and mismatch repair but not for nucleotide excision repair](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27694&geneProductId=UniProtKB:P27694)
47. [Cellular functions of human RPA1. Multiple roles of domains in replication, repair, and checkpoints](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27694&geneProductId=UniProtKB:P27694)
48. [Replication Protein A Stimulates Long Patch DNA Base Excision Repair](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27694)
49. [RPA mediates recombination repair during replication stress and is displaced from DNA by checkpoint signalling in human cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27694&geneProductId=UniProtKB:P27694)
50. [Replication protein A prevents accumulation of single-stranded telomeric DNA in cells that use alternative lengthening of telomeres](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27694&geneProductId=UniProtKB:P27694)