Relaxin family peptide receptor 1
type: Thing
description: mammalian protein found in Homo sapiens
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P361
  value: Leucine-rich repeat domain superfamily
additional property: PropertyValue
  property ID: P361
  value: LDL receptor-like superfamily
additional property: PropertyValue
  property ID: P361
  value: Relaxin receptor
additional property: PropertyValue
  property ID: P527
  value: Low-density lipoprotein (LDL) receptor class A, conserved site
additional property: PropertyValue
  property ID: P527
  value: GPCR, rhodopsin-like, 7TM
additional property: PropertyValue
  property ID: P527
  value: leucine-rich repeat, typical subtype
additional property: PropertyValue
  property ID: P637
  value: NP_001240656
additional property: PropertyValue
  property ID: P637
  value: NP_001240657
additional property: PropertyValue
  property ID: P637
  value: NP_001240658
additional property: PropertyValue
  property ID: P638
  value: 2JM4
additional property: PropertyValue
  property ID: P638
  value: 2M7P
additional property: PropertyValue
  property ID: P680
  value: G protein-coupled receptor activity
additional property: PropertyValue
  property ID: P680
  value: protein binding
additional property: PropertyValue
  property ID: P680
  value: signal transducer activity
additional property: PropertyValue
  property ID: P681
  value: integral component of membrane
additional property: PropertyValue
  property ID: P681
  value: membrane
additional property: PropertyValue
  property ID: P681
  value: plasma membrane
additional property: PropertyValue
  property ID: P682
  value: signal transduction
additional property: PropertyValue
  property ID: P682
  value: adenylate cyclase-modulating G protein-coupled receptor signaling pathway
additional property: PropertyValue
  property ID: P682
  value: G protein-coupled receptor signaling pathway
additional property: PropertyValue
  property ID: P702
  value: RXFP1
additional property: PropertyValue
  property ID: P703
  value: Homo sapiens
additional property: PropertyValue
  property ID: P705
  value: ENSP00000303248
additional property: PropertyValue
  property ID: P705
  value: ENSP00000345889
additional property: PropertyValue
  property ID: P705
  value: ENSP00000420712
confidence:
  popularity graph score:
    score: 0.002
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 11
      unique citations norm: 0.004
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 11
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: Q9HBX9
    source count: 1
    confidence: 0.2
  P361:
    value: Q24781235
    source count: 1
    confidence: 0.2
    value label: Leucine-rich repeat domain superfamily
  P361:
    value: Q41797192
    source count: 1
    confidence: 0.2
    value label: LDL receptor-like superfamily
  P361:
    value: Q24776992
    source count: 1
    confidence: 0.2
    value label: Relaxin receptor
  P361:
    value: Q83162561
    source count: 1
    confidence: 0.2
    value label: GPCR, rhodopsin-like, 7TM, protein family
  P361:
    value: Q95351433
    source count: 1
    confidence: 0.2
    value label: Low-density lipoprotein (LDL) receptor class A, conserved site, protein family
  P527:
    value: Q24781534
    source count: 1
    confidence: 0.2
    value label: Low-density lipoprotein (LDL) receptor class A, conserved site
  P527:
    value: Q24781798
    source count: 1
    confidence: 0.2
    value label: GPCR, rhodopsin-like, 7TM
  P527:
    value: Q24783125
    source count: 1
    confidence: 0.2
    value label: leucine-rich repeat, typical subtype
  P527:
    value: Q24739837
    source count: 1
    confidence: 0.2
    value label: Leucine-rich repeat
  P527:
    value: Q24775971
    source count: 1
    confidence: 0.2
    value label: low-density lipoprotein (LDL) receptor class A repeat
  P637:
    value: NP_001240656
    source count: 1
    confidence: 0.2
  P637:
    value: NP_001240657
    source count: 1
    confidence: 0.2
  P637:
    value: NP_001240658
    source count: 1
    confidence: 0.2
  P637:
    value: NP_001240659
    source count: 1
    confidence: 0.2
  P637:
    value: NP_001240661
    source count: 1
    confidence: 0.2
  P638:
    value: 2JM4
    source count: 1
    confidence: 0.2
  P638:
    value: 2M7P
    source count: 1
    confidence: 0.2
  P680:
    value: Q14859545
    source count: 3
    confidence: 0.6
    value label: G protein-coupled receptor activity
  P680:
    value: Q167149
    source count: 2
    confidence: 0.4
    value label: protein binding
  P680:
    value: Q14820643
    source count: 1
    confidence: 0.2
    value label: signal transducer activity
  P680:
    value: Q13667380
    source count: 1
    confidence: 0.2
    value label: metal ion binding

value: Q14859545
source count: 4
confidence: 0.8
value label: G protein-coupled receptor activity

value: Q14327652
source count: 2
confidence: 0.4
value label: integral component of membrane

value: Q14349455
source count: 2
confidence: 0.4
value label: membrane

value: Q29548
source count: 3
confidence: 0.6
value label: plasma membrane

value: Q3824358
source count: 1
confidence: 0.2
value label: intracellular anatomical structure

value: Q29548
source count: 2
confidence: 0.4
value label: plasma membrane

value: Q828130
source count: 2
confidence: 0.4
value label: signal transduction

value: Q14821396
source count: 1
confidence: 0.2
value label: adenylate cyclase-modulating G protein-coupled receptor signaling pathway

value: Q14758909
source count: 3
confidence: 0.6
value label: G protein-coupled receptor signaling pathway

value: Q14860468
source count: 1
confidence: 0.2
value label: adenylate cyclase-activating G protein-coupled receptor signaling pathway

value: Q14860503
source count: 1
confidence: 0.2
value label: activation of adenylate cyclase activity

value: Q18045214
source count: 1
confidence: 0.2
value label: RXFP1

value: Q15978631
source count: 1
confidence: 0.2
value label: Homo sapiens

value: ENSP00000303248
source count: 1
confidence: 0.2

value: ENSP00000345889
source count: 1
confidence: 0.2

value: ENSP00000420712
source count: 1
confidence: 0.2

value: ENSP00000434475
source count: 1
confidence: 0.2

value: ENSP00000405841
source count: 1
confidence: 0.2

source: GOA
stated in qid: Q28018111
retrieved: 2018-06-05

source: Activation of orphan receptors by the hormone relaxin
stated in qid: Q24292229
retrieved: 2018-06-05

source: C1q-tumour necrosis factor-related protein 8 (CTRP8) is a novel interaction partner of relaxin receptor RXFP1 in human brain cancer cells
stated in qid: Q44241131
retrieved: 2019-04-08

source: Sub-picomolar relaxin signalling by a pre-assembled RXFP1, AKAP79, AC2, beta-arrestin 2, PDE4D3 complex
stated in qid: Q24293265
retrieved: 2019-04-08

source: GOA
stated in qid: Q28018111
retrieved: 2019-04-08

source: Activation of orphan receptors by the hormone relaxin
stated in qid: Q24292229
retrieved: 2019-04-08

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2019-04-08

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2019-11-13

source: Q20641742
stated in qid: Q20641742
retrieved: 2020-05-30

source: Ensembl Release 99
stated in qid: Q83867711

wikidata id: Q21108186
domain: protein
level: standard
html url: https://4ort.xyz/entity/relaxin-family-peptide-receptor-1-q21108186
markdown url: https://4ort.xyz/entity/relaxin-family-peptide-receptor-1-q21108186.md
facts url summary: https://4ort.xyz/entity/relaxin-family-peptide-receptor-1-q21108186/facts.json
facts url standard: https://4ort.xyz/entity/relaxin-family-peptide-receptor-1-q21108186/facts.json
facts url full: https://4ort.xyz/entity/relaxin-family-peptide-receptor-1-q21108186/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-05T09:38:09.656675Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T13:58:50.900290+00:00Z